User profiles for Khalid A. Mohamedali

Khalid A. Mohamedali

Assistant Professor, MD Anderson Cancer Center
Verified email at mdanderson.org
Cited by 1729

PET of vascular endothelial growth factor receptor expression

W Cai, K Chen, KA Mohamedali, Q Cao… - Journal of Nuclear …, 2006 - Soc Nuclear Med
For solid tumors and metastatic lesions, tumor vascularity is a critical factor in assessing
response to therapy. Here we report the first example, to our knowledge, of 64 Cu-labeled …

Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles

…, S Lee, H Xu, AY Wang, KA Mohamedali… - Biomaterials, 2012 - Elsevier
Noninvasive imaging techniques have been considered important strategies in the clinic to
monitor tumor early response to therapy. In the present study, we applied RGD peptides …

Imaging of VEGF receptor in a rat myocardial infarction model using PET

…, L He, JC Wu, Z Li, KA Mohamedali… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Myocardial infarction (MI) leads to left ventricular (LV) remodeling, which leads to the
activation of growth factors such as vascular endothelial growth factor (VEGF). However, the …

Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel

…, W Cai, A Veeravagu, KA Mohamedali… - Journal of Nuclear …, 2007 - Soc Nuclear Med
Vascular endothelial growth factor A (VEGF-A) and its receptors, Flt-1/FLT-1 (VEGFR-1) and
Flk-1/KDR (VEGFR-2), are key regulators of tumor angiogenesis and tumor growth. The …

[HTML][HTML] The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment

…, S Ekmekcioglu, JW Marks, KA Mohamedali… - Journal of Investigative …, 2013 - Elsevier
Fibroblast growth factor-inducible protein 14 (Fn14), the cell surface receptor for tumor necrosis
factor-like weak inducer of apoptosis (TWEAK), is overexpressed in various human solid …

[HTML][HTML] The highest levels of purine catabolic enzymes in mice are present in the proximal small intestine.

KA Mohamedali, OM Guicherit, RE Kellems… - Journal of Biological …, 1993 - Elsevier
Recent studies on the tissue distribution and developmental regulation of adenosine deaminase
(ADA) activity in mice show that very high ADA levels exist in the murine alimentary tract …

Noncovalent functionalization of carbon nanovectors with an antibody enables targeted drug delivery

JM Berlin, TT Pham, D Sano, KA Mohamedali… - ACS …, 2011 - ACS Publications
Current chemotherapeutics are characterized by efficient tumor cell-killing and severe side
effects mostly derived from off-target toxicity. Hence targeted delivery of these drugs to tumor …

Cell-targeting fusion constructs containing recombinant gelonin

MA Lyu, YJ Cao, KA Mohamedali… - Methods in enzymology, 2012 - Elsevier
Therapeutic agents capable of targeting tumor cells present as established tumors and
micrometastases have already demonstrated their potential in clinical trials. Immunotoxins …

Sensitive angiogenesis imaging of orthotopic bladder tumors in mice using a selective magnetic resonance imaging contrast agent containing VEGF121/rGel

EJ Cho, J Yang, KA Mohamedali, EK Lim… - Investigative …, 2011 - journals.lww.com
Objectives: To investigate the efficiency of magnetic resonance imaging (MRI) contrast agents
employing vascular endothelial growth factor (VEGF 121)/rGel conjugated MnFe 2 O 4 …

Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase

V Sideraki, KA Mohamedali, DK Wilson, Z Chang… - Biochemistry, 1996 - ACS Publications
Two adjacent aspartates, Asp 295 and Asp 296, playing major roles in the reaction catalyzed
by mouse adenosine deaminase (mADA) were altered using site-directed mutagenesis. …