The ABC drug transporters, including ABCG2, are well known for their ability to efflux a wide
spectrum of chemotherapeutic agents, thereby conferring a multidrug-resistant phenotype. …

ABCG2 is an ATP-binding-cassette (ABC) transporter that confers multidrug resistance (MDR)
to tumor cells by extruding a broad variety of chemotherapeutic agents, ultimately leading …

Alternative splicing of pre-mRNA contributes significantly to human proteomic complexity,
playing a key role in development, gene expression and, when aberrant, human disease onset…

We have previously reported that the methylxanthine caffeine increases expression of the
splicing factor SRSF2, the levels of which are normally controlled by a negative autoregulatory …

Black male teachers make up less than 2% of the American public school labor force (Brockenbrough,
2008; Dee, 2005; Lewis, 2007). We know little about their life histories and …

319 A growing body of data indicates that cancer cells often express specific alternatively
spliced transcripts. For example, several members of the Wnt/β-catenin pathway have been …

2575 Alternative pre-mRNA splicing adds to the complexity of gene expression by producing
multiple splice variants from one single gene. Importantly, splice variants involved in …

… Jia Shi and Kirk Pabon, for their constant help and support during my graduate career. Dr. …
used throughout my tenure in the lab, and Kirk has been an enormous source of technical and …

A major limitation to the successful chemotherapeutic treatment of cancer is the resistance of
tumor cells to cytotoxic drugs. Multidrug resistance is cellular resistance to a wide range of …

… Johnson, Barbara Gorfajn, Debbie Friedman, Roshni Mody, and Kirk Pabon, for their
help and friendship that accompanied me during the up and downs of my graduate school. …