User profiles for Krishna R. Kalari
 | Krishna Rani KalariAssociate Professor, Mayo Clinic Verified email at mayo.edu Cited by 8680 |
COVID-19 transmission, current treatment, and future therapeutic strategies
At the stroke of the New Year 2020, COVID-19, a zoonotic disease that would turn into a
global pandemic, was identified in the Chinese city of Wuhan. Although unique in its …
global pandemic, was identified in the Chinese city of Wuhan. Although unique in its …
Protein kinase Cι expression and oncogenic signaling mechanisms in cancer
Accumulating evidence demonstrates that PKCι is an oncogene and prognostic marker that
is frequently targeted for genetic alteration in many major forms of human cancer. Functional …
is frequently targeted for genetic alteration in many major forms of human cancer. Functional …
[HTML][HTML] Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls
Multiple sclerosis (MS) is an immune-mediated disease, the etiology of which involves both
genetic and environmental factors. The exact nature of the environmental factors responsible …
genetic and environmental factors. The exact nature of the environmental factors responsible …
[PDF][PDF] FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt
Akt is a central regulator of cell growth. Its activity can be negatively regulated by the phosphatase
PHLPP that specifically dephosphorylates the hydrophobic motif of Akt (Ser473 in Akt1…
PHLPP that specifically dephosphorylates the hydrophobic motif of Akt (Ser473 in Akt1…
[PDF][PDF] Longitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome
The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI)
disorders. Determining its mechanistic role in disease has been difficult due to apparent …
disorders. Determining its mechanistic role in disease has been difficult due to apparent …
[HTML][HTML] The microbiome of aseptically collected human breast tissue in benign and malignant disease
…, J Xiao, DC Radisky, KL Knutson, KR Kalari… - Scientific reports, 2016 - nature.com
Globally breast cancer is the leading cause of cancer death among women. The breast
consists of epithelium, stroma and a mucosal immune system that make up a complex …
consists of epithelium, stroma and a mucosal immune system that make up a complex …
[HTML][HTML] MAP-RSeq: Mayo analysis pipeline for RNA sequencing
KR Kalari, AA Nair, JD Bhavsar, DR O'Brien… - BMC …, 2014 - Springer
… In our source code for MAP-RSeq pipeline, we have Perl, R scripts and instructions that can be
used post … Krishna R Kalari … Krishna R Kalari, Asha A Nair contributed equally to this work. …
used post … Krishna R Kalari … Krishna R Kalari, Asha A Nair contributed equally to this work. …
[HTML][HTML] Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group n9831 Adjuvant …
… Krishna R. Kalari … Subramanian J, Simon R. An evaluation of resampling methods for
assessment of survival risk prediction in high-dimensional settings. Stat Med. …
assessment of survival risk prediction in high-dimensional settings. Stat Med. …
[HTML][HTML] DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine
Triple-negative breast cancer (TNBC) is a heterogeneous disease with poor prognosis that
lacks targeted therapies, especially in patients with chemotherapy-resistant disease. Since …
lacks targeted therapies, especially in patients with chemotherapy-resistant disease. Since …
[HTML][HTML] Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing
We used deep sequencing technology to profile the transcriptome, gene copy number, and
CpG island methylation status simultaneously in eight commonly used breast cell lines to …
CpG island methylation status simultaneously in eight commonly used breast cell lines to …