The dermis is primarily composed of the extracellular matrix (ECM) and fibroblasts. During
the aging process, the dermis undergoes significant changes. Collagen, which is a major …

Elucidation of the physiologically distinct subunits of troponin in 1973 greatly facilitated our
understanding of cardiac contraction. Although troponins are expressed in both skeletal and …

N-myc down-regulated gene 1 (NDRG1) is a known metastasis suppressor in multiple cancers,
being also involved in embryogenesis and development, cell growth and differentiation, …

To the best of our knowledge, no study has been conducted to date to directly compare the
collagen metabolism of photoaged and naturally aged human skin. In this study, we …

Organisms must be able to respond to low oxygen in a number of homeostatic and pathological
contexts. Regulation of hypoxic responses via the hypoxia-inducible factor (HIF) is well …

This is a comprehensive study of the changes in major antioxidant enzymes and antioxidant
molecules during intrinsic aging and photoaging processes in the epidermis and dermis of …

Background Severe wrinkles and pigmentary changes of the exposed skin indicate substantial
damage due to UV radiation. Many investigators believe that the principal manifestation …

A fundamental variable in culture medium is its pH, which must be controlled by an appropriately
formulated buffering regime, since biological processes are exquisitely sensitive to acid…

Silver sulfadiazine (Ag-SD) is a useful antibacterial agent for wound treatment. However,
recent findings indicate that the compound delays the wound-healing process. That delay may …

Aims Emipagliflozin (EMPA) is a potent inhibitor of the renal sodium-glucose co-transporter
2 (SGLT2) and an effective treatment for type-2 diabetes. In patients with diabetes and heart …