[PDF][PDF] Influence of sulfhydryl reagents and heavy metals on the functional state of the muscarinic acetylcholine receptor in rat brain
RS ARONSTAM, LEOG ABOOD, W HOSS - Molecular Pharmacology, 1978 - Citeseer
ARONSTAM, ROBERT S., ABOOD, LEO G. & Hoss, WAYNE(1978) Influence of sulfhydryl
reagents and heavy metals on the functional state of the muscarinic acetylcholine receptor …
reagents and heavy metals on the functional state of the muscarinic acetylcholine receptor …
Stereoselective muscarinic acetylcholine and opiate receptors in human phagocytic leukocytes
A Lopker, LG Abood, W Hoss, FJ Lionetti - Biochemical pharmacology, 1980 - Elsevier
Human granulocytes and monocytes exhibited stereospecific, high-affinity binding to 3-quinuclidinyl
benzilate (QNB) and dihydromorphine (DHM), specific ligands for the muscarinic …
benzilate (QNB) and dihydromorphine (DHM), specific ligands for the muscarinic …
Synthesis of the first highly potent bridged nicotinoid 9-Azabicyclo [4.2. 1] nona [2, 3-c] pyridine (pyrido [3, 4-b] homotropane)
…, MT Cheng, LC Mutter, LG Abood - Journal of the …, 1986 - ACS Publications
The semirigid alkaloid anatoxin a (3) 3 is known to possess high activity at the nicotinic
acetylcholine receptor. 4 Nornicotine (la), a potent agonist in its own right, has an activity …
acetylcholine receptor. 4 Nornicotine (la), a potent agonist in its own right, has an activity …
Synthesis and biological characterization of pyridohomotropanes. Structure-activity relationships of conformationally restricted nicotinoids
DB Kanne, LG Abood - Journal of medicinal chemistry, 1988 - ACS Publications
The recently discovered nicotinic agonist pyrido [3, 4-b] homotropane (PHT) as well as its N-methyl
and 2'-meihyl derivatives (syntheses reported herein) were compared with nicotine, …
and 2'-meihyl derivatives (syntheses reported herein) were compared with nicotine, …
Central Stimulants. II. Cholinergic Blocking Agents1
JH BIEL, LEOG ABOOD, WK HOYA… - The Journal of …, 1961 - ACS Publications
The initial finding that certain disubstituted glycolates of 3-hydroxypiperidine could elicit
potent psychotomimetic and antidepressant effects in man suggested a possible relationship …
potent psychotomimetic and antidepressant effects in man suggested a possible relationship …
Structure–activity relationships for nicotine analogs comparing competition for [3H]nicotine binding and psychotropic potency
…, TS Osdene, LG Abood - Drug development …, 1998 - Wiley Online Library
… This posthumous publication is in memory of Leo G. Abood, Professor of Biochemistry and
Pharmacology, University of Rochester, born 1922, died 1998, and distinguished for his many …
Pharmacology, University of Rochester, born 1922, died 1998, and distinguished for his many …
Binding of optically pure (−)-[3H] nicotine to rat brain membranes
LG Abood, S Grassi, M Costanza - FEBS letters, 1983 - Elsevier
With the recent availability of (−)-[ 3 H]nicotine of high specific activity, binding studies were
performed on rat brain membranes in the presence of a variety of nicotine analogues and …
performed on rat brain membranes in the presence of a variety of nicotine analogues and …
Purification of the opiate receptor from rat brain.
JM Bidlack, LG Abood… - Proceedings of the …, 1981 - National Acad Sciences
The opiate receptor was purified from a Triton-solubilized preparation of rat neural membranes
by the use of affinity chromatography. The affinity gel was prepared by coupling 14-beta-…
by the use of affinity chromatography. The affinity gel was prepared by coupling 14-beta-…
[3H] Mecamylamine binding to rat brain membranes: studies with mecamylamine and nicotine analogues
S Banerjee, JS Punzi, K Kreilick, LG Abood - Biochemical pharmacology, 1990 - Elsevier
Mecamylamine, an antagonist to nicotine, does not compete at the nicotinic recognition site,
but is believed to block the ion channel of the nicotinic receptor. The present study …
but is believed to block the ion channel of the nicotinic receptor. The present study …
Conversion between configurational states of the muscarinic receptor in rat brain
RS Aronstam, W Hoss, LG Abood - European Journal of Pharmacology, 1977 - Elsevier
Reductive alkylation of neural membranes by N-ethyl malemide (NEM) converts muscarinic
acetylcholine receptors from a state of low to high affinity for receptor agonists. Interactions of …
acetylcholine receptors from a state of low to high affinity for receptor agonists. Interactions of …