Update on human herpesvirus 6 biology, clinical features, and therapy

L De Bolle, L Naesens, E De Clercq - Clinical microbiology …, 2005 - Am Soc Microbiol
Human herpesvirus 6 (HHV-6) is a betaherpesvirus that is closely related to human
cytomegalovirus. It was discovered in 1986, and HHV-6 literature has expanded considerably in the …

Antiviral agents active against human herpesviruses HHV‐6, HHV‐7 and HHV‐8

E De Clercq, L Naesens, L De Bolle… - Reviews in medical …, 2001 - Wiley Online Library
A series of antiviral compounds were examined for their activity against human herpesvirus
type 6 (HHV‐6), type 7 (HHV‐7) and type 8 (HHV‐8). They were selected either because …

COPD management in primary care: an observational, community pharmacy–based study

…, E Adriaens, LV Bortel, LD Bolle… - Annals of …, 2010 - journals.sagepub.com
Background: Chronic obstructive pulmonary disease (COPD) is a prevalent disease that is
frequently treated in primary care. However, data regarding the primary care management of …

Effectiveness of pharmacist intervention for asthma control improvement

E Mehuys, L Van Bortel, L De Bolle… - European …, 2008 - Eur Respiratory Soc
Education on optimal medication use is an essential strategy to improve asthma control. The
current authors investigated whether pharmacist interventions, focused on appropriate use …

Self-medication of upper gastrointestinal symptoms: a community pharmacy study

E Mehuys, LV Bortel, LD Bolle… - Annals of …, 2009 - journals.sagepub.com
Background Upper gastrointestinal (GI) symptoms are a common reason for self-treatment
with over-the-counter (OTC) medication. However, data are scarce on the typology of GI …

Home medication cabinets and self-medication: a source of potential health threats?

L De Bolle, E Mehuys, E Adriaens… - Annals of …, 2008 - journals.sagepub.com
BACKGROUND: Data regarding the contents of home medication cabinets (HMCs), the
management of leftover medications, and the inclination of patients toward self-initiated …

Effectiveness of a community pharmacist intervention in diabetes care: a randomized controlled trial

E Mehuys, L Van Bortel, L De Bolle… - Journal of clinical …, 2011 - Wiley Online Library
What is known and Objective: There is little evidence from well‐designed randomized controlled
trials of the impact of community pharmacist intervention on the clinical management of …

Quantitative analysis of human herpesvirus 6 cell tropism

L De Bolle, J Van Loon, E De Clercq… - Journal of medical …, 2005 - Wiley Online Library
Although HHV‐6A and ‐6B are known to replicate preferably in human T‐lymphocytes, in
vitro infection of several other cell types has been described. Also, the finding that both …

Self‐medication of regular headache: a community pharmacy‐based survey

…, I Van Tongelen, L De Bolle… - European journal of …, 2012 - Wiley Online Library
Background: This observational community pharmacy‐based study aimed to investigate
headache characteristics and medication use of persons with regular headache presenting for …

Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423

L De Bolle, G Andrei, R Snoeck, Y Zhang… - Biochemical …, 2004 - Elsevier
CMV423 (2-chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide) is a new
antiviral agent with potent and selective in vitro activity against the β-herpesvirus human …