Mechanisms by which the dithiol chelating agent 2,3-dimercaptopropane-1-sulfonate (DMPS)
significantly alters the renal tubular transport, accumulation, and toxicity of inorganic …

This study was designed to examine the synthesis and possible secretion of glutathione (GSH)
in the S 1 , S 2 , and S 3 segments of the rabbit proximal tubule. GSH synthesis and …

In the first of two sets of experiments, the lumen-to-cell and cell-to-bath transport rates for
glycine were measured in the isolated-perfused medullary pars recta (S3 cells) of the rabbit …

This article describes a laboratory protocol for a multiweek project piloted in a new upper-level
biology laboratory (BIO 426) using cell culture techniques. Human embryonic kidney-293 …

Lumen-to-bath and bath-to-lumen transport rates of glutathione (GSH) were measured in
isolated perfused S 1, S 2, and S 3 segments of the rabbit proximal tubule. In lumen-to-bath …

The TH!NK Program is an initiative designed to cultivate students' higher order skills in
critical and creative thinking at North Carolina State University. Faculty across the university …

The TH! NK Program is an initiative designed to cultivate students’ higher order skills in
critical and creative thinking at North Carolina State University. Faculty across the university …

In the course of a high throughput screen to search for ligands of peroxisome proliferator
activated receptor-γ (PPARγ), we identified GW9662 using a competition binding assay against …

… The isoxazole library was screened at a concentration of 1 μM using the cell-free FXR
LiSA, 8 and 37 compounds were identified with activity equal to 50 μM CDCA. The active …

… LiSA at 1 μM. Six carboxamides (6−11) were identified from the array with activity less than 1
μM in the LXRα/SRC1 LiSA … 50 of 45 nM in the LXRα/SRC1 LiSA. As was seen in the earlier …