The pharmacokinetics of depot antipsychotic medications are such that an intramuscular
injection given at intervals of from 1 to 4 weeks will produce adequate plasma concentrations …

The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, dosage, and cost of
the atypical antipsychotic drug clozapine are reviewed. Clozapine is a dibenzazepine …

A patient with prominent apathy secondary to multiple subcortical infarcts was treated
successfully with methylphenidate. SPECT and reaction time testing showed selective …

Fifty-nine plasma thiothixene concentrations were measured in 42 patients as part of routine
therapeutic drug monitoring. Data collection included concomitant medications, smoking …

Current concepts of schizophrenia and its treatment are discussed. Schizophrenia entails
negative symptoms, such as behavioral and cognitive deficits, attributed to loss of normal …

Because brain serotonin levels depend directly on the amounts of exogenous tryptophan (TRP)
available for its synthesis, amounts of TRP in the diet may be manipulated to alter the …

… He read in a journal that Watanabe performed an arthroscopy [ 9 ]. To learn the … Watanabe
would be happy to see the application of endoscopy. For his contributions, I believe Watanabe …

Background Although vascular endothelial growth factor (VEGF) is a primary mediator of
retinal angiogenesis, VEGF inhibition alone is insufficient to prevent retinal neovascularization. …

The in vitro metabolism of phenelzine (2-phenylethylhydrazine) by phenobarbital-pretreated
rat liver microsomes yields ethylbenzene, 2-phenylethanol, 2-phenylacetaldehyde, …

Recently there has been an increase in the diagnosis of major depressive disorder (MDD)
in schoolaged chiidren and adolescents. MDD can be triggered by multiple Stressors and …