Gastric cancer is the third leading cause of cancer-related deaths worldwide. Over 95% of
gastric cancers are adenocarcinomas, which are typically classified based on anatomic …

Oesophageal carcinoma affects more than 450 000 people worldwide and the incidence is
rapidly increasing. Squamous-cell carcinoma is the predominant form of oesophageal …

Ancient and diverse antibiotic resistance genes (ARGs) have previously been identified
from soil 1 , 2 , 3 , including genes identical to those in human pathogens 4 . Despite the …

The bacteria that colonize humans and our built environments have the potential to influence
our health. Microbial communities associated with seven families and their homes over 6 …

Antibiotic resistance is a dire clinical problem with important ecological dimensions. While
antibiotic resistance in human pathogens continues to rise at alarming rates, the impact of …

Purpose There are no approved treatments for recurrent/metastatic head and neck squamous
cell carcinoma refractory to platinum and cetuximab. In the single-arm, phase II KEYNOTE-…

Purpose To determine the response rate, survival and toxicity of infusional cisplatin plus
fluorouracil (CF) versus cisplatin plus paclitaxel (CP) in patients with incurable squamous cell …

Abstract Development of the preterm infant gut microbiota is emerging as a critical research
priority 1. Since preterm infants almost universally receive early and often extended …

The p53 tumor suppressor gene product is a transcriptional transactivator and a potent
apoptotic inducer. The fact that many of the DNA tumor virus oncoproteins bind to p53 and affect …

OBJECTIVES: Esophagectomy is the standard treatment for T1 esophageal cancer (EC).
Interest in endoscopic therapies, particularly for T1 EC, is increasing. We evaluated the long-…