User profiles for M Mousli

Mousli M

Université de Strasbourg
Verified email at unistra.fr
Cited by 5882

G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides

M Mousli, JL Bueb, C Bronner, B Rouot… - Trends in pharmacological …, 1990 - cell.com
The neuropeptide substance P, the venom peptide mastoparan and the synthetic polyamine
compound 48/80 activate rat peritoneal mast cells, leading to rapid histamine release by …

[HTML][HTML] Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer …

M Alhosin, T Sharif, M Mousli… - Journal of Experimental …, 2011 - Springer
… Furthermore, very recently, it was shown that UHRF1 down-regulation in p53 containing and
deficient cancer cells induced cell cycle arrest in G2/M and caspase-8-dependent apoptosis …

[HTML][HTML] Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer

…, AL Al-Malki, H Choudhry, M Mousli… - Journal of Experimental …, 2016 - Springer
Epigenetic silencing of tumor suppressor genes (TSGs) through DNA methylation and histone
changes is a main hallmark of cancer. Ubiquitin-like with PHD and RING Finger domains …

GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain.

L De Vries, M Mousli, A Wurmser… - Proceedings of the …, 1995 - National Acad Sciences
Using the yeast two-hybrid system we have identified a human protein, GAIP (G Alpha
Interacting Protein), that specifically interacts with the heterotrimeric GTP-binding protein G alpha …

ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIα expression

R Hopfner, M Mousli, JM Jeltsch, A Voulgaris, Y Lutz… - Cancer research, 2000 - AACR
The one-hybrid system with an inverted CCAAT box as the DNA target sequence was used
to identify proteins acting on key DNA sequences of the promoter of the topoisomerase IIα …

[HTML][HTML] ICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cells

M Mousli, R Hopfner, AQ Abbady, D Monte… - British journal of …, 2003 - nature.com
ICBP90 (Inverted CCAAT box Binding Protein of 90 kDa) is a recently identified nuclear
protein that binds to one of the inverted CCAAT boxes of the topoisomerase IIα (TopoIIα) gene …

Down‐regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1‐dependent DNA‐damage checkpoint signals contributes to cell cycle arrest at G1/S transition

Y Arima, T Hirota, C Bronner, M Mousli… - Genes to …, 2004 - Wiley Online Library
… To inhibit ATM-dependent DNA damage signals, cells were pretreated with 5 mm caffeine
for 1 h and then incubated with adriamycin (500 ng/ml). Whole cell extracts were subjected to …

[HTML][HTML] Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center

L Brino, A Urzhumtsev, M Mousli, C Bronner… - Journal of Biological …, 2000 - ASBMB
… The GST 43-kDa fusion protein (5 μm) was … (40 μm) in the presence or absence of ADPNP
(0.5 mm) for various times at 25 C in 35 mm Tris-HCl, pH 7.3, 24 mm KCl, 6 mm MgCl 2 , 5 mm

The retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1/S transition during the cell cycle

M Jeanblanc, M Mousli, R Hopfner, K Bathami… - Oncogene, 2005 - nature.com
… min and resuspended in 200 μl of 50 mM Tris, pH 8.0, 5 mM EDTA, 1% SDS (supplemented …
10 times in 50 mM Tris, pH 8.0, 0.5 mM EDTA, 0.5% NP-40 and 0.2 M NaCl. Extracts were …

Direct activation of GTP-binding regulatory proteins (G-proteins) by substance P and compound 48/80

M Mousli, C Bronner, Y Landry, J Bockaert, B Rouot - FEBS letters, 1990 - Elsevier
The neuropeptide substance P and the polyamine compound 48 80 , both known to activate
mast cell secretory processes, increased the rate of GTP γ S binding to G-proteins purified …