5-HT receptor regulation of neurotransmitter release
KB Fink, M Göthert - Pharmacological reviews, 2007 - ASPET
Serotoninergic neurons in the central nervous system impinge on many other neurons and
modulate their neurotransmitter release. This review focuses on 1) the function of presynaptic …
modulate their neurotransmitter release. This review focuses on 1) the function of presynaptic …
Modulation of neurotransmitter release by presynaptic autoreceptors
K Starke, M Gothert, H Kilbinger - Physiological reviews, 1989 - journals.physiology.org
The term “presynaptic receptor” seems to have been used first by Riker et al.(547) for a site
of action of quaternary ammonium compounds on motor nerve terminals. Eighteen years later…
of action of quaternary ammonium compounds on motor nerve terminals. Eighteen years later…
Inhibition of neuronal Ca2+ influx by gabapentin and pregabalin in the human neocortex
…, S Duffy, H Clusmann, M Göthert - …, 2002 - Elsevier
… Neocortical tissue was homogenized with a Potter–Elvehjem glass homogenizer (800
rpm, 6 strokes/2 min) in 40 vol (wt/vol) of 0.32 M sucrose. The homogenate was centrifuged at …
rpm, 6 strokes/2 min) in 40 vol (wt/vol) of 0.32 M sucrose. The homogenate was centrifuged at …
Direct inhibition by cannabinoids of human 5‐HT3A receptors: probable involvement of an allosteric modulatory site
…, H Bönisch, BW Urban, M Göthert - British journal of …, 2002 - Wiley Online Library
… of 3 μM CP55940. Competition studies were carried out using [ 3 H]-GR65630 (10 nM) and
up … under study, ranging from 1 nM up to 100 μM. Protein concentration was measured by the …
up … under study, ranging from 1 nM up to 100 μM. Protein concentration was measured by the …
Modulation of neurotransmitter release via histamine H3 heteroreceptors
…, M Kathmann, M Göthert - Fundamental & …, 1994 - Wiley Online Library
… Gothert M. Inhibition of noradrenaline release via NEM-sensitive H, receptors in the mouse
brain … Detzner M. Gothert M. Histamine inhibits dopamine release in the mouse striatum viu …
brain … Detzner M. Gothert M. Histamine inhibits dopamine release in the mouse striatum viu …
Characterization of the novel human serotonin receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E
…, H Bönisch, M Göthert, G Rappold, M Brüss - Molecular …, 2007 - ASPET
Within the family of serotonin receptors, the 5-hydroxytryptamine-3 (5-HT 3 ) receptor is the
only ligand-gated ion channel. It is composed of five subunits, of which the 5-HT 3A and 5-HT …
only ligand-gated ion channel. It is composed of five subunits, of which the 5-HT 3A and 5-HT …
Inhibition of neuronal Ca2+ influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices
…, W Meder, DJ Dooley, M Göthert - British journal of …, 2000 - Wiley Online Library
… 30 mM). The release of the endogenous excitatory amino acids glutamate and aspartate was
evoked by K + (50 mM… by K + (15 and 25 mM) and measured by liquid scintillation counting. …
evoked by K + (50 mM… by K + (15 and 25 mM) and measured by liquid scintillation counting. …
Cannabinoid CB1 receptor-mediated inhibition of noradrenaline release in the human and guinea-pig hippocampus
E Schlicker, J Timm, J Zentner, M Göthert - … -Schmiedeberg's archives of …, 1997 - Springer
We examined the question of whether cannabinoid receptors modulating noradrenaline
release are detectable in the brain of humans and experimental animals. For this purpose, …
release are detectable in the brain of humans and experimental animals. For this purpose, …
SB-216641 and BRL-15572–compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors
…, LJ Collin, M Duckworth, L Gaster, M Göthert… - Naunyn-Schmiedeberg's …, 1997 - Springer
Despite only modest homology between h5-HT 1B and h5-HT 1D receptor amino acid
sequences, these receptors display a remarkably similar pharmacology. To date there are few …
sequences, these receptors display a remarkably similar pharmacology. To date there are few …
Anandamide and methanandamide induce both vanilloid VR1- and cannabinoid CB1 receptor-mediated changes in heart rate and blood pressure in anaesthetized …
B Malinowska, G Kwolek, M Göthert - Naunyn-Schmiedeberg's archives of …, 2001 - Springer
In anaesthetized rats activation of vanilloid receptors on sensory vagal nerves elicits rapid
bradycardia and hypotension (Bezold-Jarisch reflex). Recent in vitro experiments revealed …
bradycardia and hypotension (Bezold-Jarisch reflex). Recent in vitro experiments revealed …