MicroRNAs in cancer
G Di Leva, M Garofalo, CM Croce - Annual Review of Pathology …, 2014 - annualreviews.org
MicroRNAs (miRNAs) are small noncoding RNAs that typically inhibit the translation and
stability of messenger RNAs (mRNAs), controlling genes involved in cellular processes such as …
stability of messenger RNAs (mRNAs), controlling genes involved in cellular processes such as …
miR221/222 in cancer: their role in tumor progression and response to therapy
M Garofalo, C Quintavalle, G Romano… - Current molecular …, 2012 - ingentaconnect.com
miRNAs are small non-coding RNAs of ~24 nt that can block mRNA translation and/or negatively
regulate its stability. There is a large body of evidence that dysregulation of miRNAs is …
regulate its stability. There is a large body of evidence that dysregulation of miRNAs is …
microRNAs: Master regulators as potential therapeutics in cancer
M Garofalo, CM Croce - Annual review of pharmacology and …, 2011 - annualreviews.org
It has been demonstrated that all the known processes involved in cancer, including apoptosis,
proliferation, survival, and metastasis, are regulated by small regulatory noncoding RNAs …
proliferation, survival, and metastasis, are regulated by small regulatory noncoding RNAs …
[PDF][PDF] RETRACTED: miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation
M Garofalo, G Di Leva, G Romano, G Nuovo, SS Suh… - Cancer cell, 2009 - cell.com
Lung and liver cancers are among the most deadly types of cancer. Despite improvements
in treatment over the past few decades, patient survival remains poor, underlining the need …
in treatment over the past few decades, patient survival remains poor, underlining the need …
Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin
R Garzon, M Garofalo, MP Martelli… - Proceedings of the …, 2008 - National Acad Sciences
Acute myeloid leukemia (AML) carrying NPM1 mutations and cytoplasmic nucleophosmin (NPMc+
AML) accounts for about one-third of adult AML and shows distinct features, including …
AML) accounts for about one-third of adult AML and shows distinct features, including …
[PDF][PDF] RETRACTED: downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development
…, DM Benson, C Hofmainster, H Alder, M Garofalo… - Cancer cell, 2010 - cell.com
In multiple myeloma (MM), an incurable B cell neoplasm, mutation or deletion of p53 is rarely
detected at diagnosis. Using small-molecule inhibitors of MDM2, we provide evidence that …
detected at diagnosis. Using small-molecule inhibitors of MDM2, we provide evidence that …
Pulmonary nontuberculous mycobacterial disease: prospective study of a distinct preexisting syndrome
…, R Claypool, DM Hilligoss, M Garofalo… - American journal of …, 2008 - atsjournals.org
… A total of 46 were infected with Mycobacterium avium complex, M. xenopi, or M. kansasii;
17 were infected with rapidly growing mycobacteria. Female patients were significantly taller (…
17 were infected with rapidly growing mycobacteria. Female patients were significantly taller (…
RETRACTED ARTICLE: EGFR and MET receptor tyrosine kinase–altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers
The involvement of the MET oncogene in de novo and acquired resistance of non-small cell
lung cancers (NSCLCs) to tyrosine kinase inhibitors (TKIs) has previously been reported, …
lung cancers (NSCLCs) to tyrosine kinase inhibitors (TKIs) has previously been reported, …
MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer
M Garofalo, C Quintavalle, G Di Leva, C Zanca… - Oncogene, 2008 - nature.com
To define novel pathways that regulate susceptibility to tumor necrosis factor (TNF)-related
apoptosis-inducing ligand (TRAIL) in non-small cell lung cancer (NSCLC), we have …
apoptosis-inducing ligand (TRAIL) in non-small cell lung cancer (NSCLC), we have …
Reprogramming of miRNA networks in cancer and leukemia
…, M Previati, S Ambs, T Palumbo, M Garofalo… - Genome …, 2010 - genome.cshlp.org
We studied miRNA profiles in 4419 human samples (3312 neoplastic, 1107 nonmalignant),
corresponding to 50 normal tissues and 51 cancer types. The complexity of our database …
corresponding to 50 normal tissues and 51 cancer types. The complexity of our database …