Pannexin1 (Panx1) channels are ubiquitously expressed in vertebrate cells and are widely
accepted as adenosine triphosphate (ATP)-releasing membrane channels. Activation of …

Study of α6β4 nicotinic acetylcholine receptors (nAChRs) as a pharmacological target has
recently gained interest because of their involvement in analgesia, control of catecholamine …

Introduction Cell-free plasma mitochondrial DNA (mt-DNA) and nuclear DNA (n-DNA) are
biomarkers with prognostic utility in conditions associated with a high rate of cell death. This …

BACKGROUND: Diagnosing patients with acute mesenteric ischemia (AMI) in the emergency
ward is challenging. This study assesses the usefulness of plasma DNA in patients with …

Nicotine in tobacco is known to induce tumor-promoting effects and cause chemotherapy
resistance through the activation of nicotinic acetylcholine receptors (nAChRs). Many studies …

While P2X7 receptor expression on tumour cells has been characterized as a promotor of
cancer growth and metastasis, its expression by the host immune system is central for …

Interleukin-1β (IL-1β) is an important cytokine that modulates peripheral and central pain
sensitization at the spinal level. Among its effects, it increases spinal cord excitability by …

Dysferlin is a transmembrane C-2 domain-containing protein involved in vesicle trafficking
and membrane remodeling in skeletal muscle cells. However, the mechanism by which …

Although 2D in vitro cancer cell cultures have been used for decades as a first line-of-research
tool to investigate antitumoral drugs and treatments, their use presents many drawbacks, …

INTRODUCTION: Plasma vascular endothelial growth factor (VEGF) was shown to increase
during acute hypoglycemia and could mediate rapid adaptation of the brain. In this study we …