The orphan G protein–coupled receptor 3 modulates amyloid-beta peptide generation in neurons

A Thathiah, K Spittaels, M Hoffmann, M Staes, A Cohen… - Science, 2009 - science.org
Deposition of the amyloid-β peptide is a pathological hallmark of Alzheimer's disease. A
high-throughput functional genomics screen identified G protein–coupled receptor 3 (GPR3), a …

A modelling method for the development of groupware applications as socio-technical systems

T Herrmann, M Hoffmann, G Kunau… - Behaviour & Information …, 2004 - Taylor & Francis
Special methodological approaches are needed, particularly in the area of modelling, to
develop socio-technical systems in the field of CSCW. Engineering tasks and the development …

Coherent automotive radar networks: The next generation of radar-based imaging and mapping

M Gottinger, M Hoffmann, M Christmann… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
Imaging radar is a key perception technology for automotive and industrial applications. A
lot of progress has been made with high channel count systems, deploying, for example, 12 …

A realistic radar ray tracing simulator for large MIMO-arrays in automotive environments

C Schüßler, M Hoffmann, J Bräunig… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
With the rise of high resolution multiple input multiple output (MIMO) systems, radar became
an important sensor in the development of Advanced Driver Assistance Systems (ADAS) …

A tale of three security operation centers

…, J Case, T Truong, L Zomlot, M Hoffmann - Proceedings of the …, 2014 - dl.acm.org
Security researchers have been trying to understand functioning of a security operation center
(SOC) and how security analysts perform their job. This effort is motivated by the fact that …

Adenoviral vectors expressing siRNAs for discovery and validation of gene function

…, S Herman, R Brys, K Thys, M Hoffmann… - Genome …, 2003 - genome.cshlp.org
RNA interference is a powerful tool for studying gene function and for drug target discovery
in diverse organisms and cell types. In mammalian systems, small interfering RNAs (siRNAs), …

Tackling Industrial Downtimes with Artificial Intelligence in Data-Driven Maintenance

MA Hoffmann, R Lasch - ACM Computing Surveys, 2023 - dl.acm.org
The application of Artificial Intelligence (AI) approaches in industrial maintenance for fault
detection and prediction has gained much attention from scholars and practitioners. This …

First enantioselective catalytic Wittig reaction

T Werner, M Hoffmann… - European Journal of …, 2014 - Wiley Online Library
Herein we present the first catalytic enantioselective Wittig reaction. Chiral mono‐ and
diphosphines were employed as catalysts for the desymmetrization of a prochiral ketone. The …

Pedestrian classification for 79 GHz automotive radar systems

R Prophet, M Hoffmann, A Ossowska… - 2018 IEEE Intelligent …, 2018 - ieeexplore.ieee.org
Radar sensors have become an integral part of advanced driver assistance systems. Merely
detecting targets will not, however, advance their contribution. Rather, an object …

Discovery of naturally occurring splice variants of the rat histamine H3 receptor that act as dominant-negative isoforms

…, FC Shenton, G Drutel, K Karlstedt, M Hoffmann… - Molecular …, 2006 - ASPET
We described previously the cDNA cloning of three functional rat histamine H 3 receptor (rH
3 R) isoforms as well as the differential brain expression patterns of their corresponding …