User profiles for Marco Weiergräber
Prof. Dr. Dr. Marco WeiergräberFederal Institute for Drugs and Medical Devices, Bundesinstitut für Arzneimittel und … Verified email at bfarm.de Cited by 2853 |
Block of cloned human T-type calcium channels by succinimide antiepileptic drugs
JC Gomora, AN Daud, M Weiergräber… - Molecular …, 2001 - ASPET
Inhibition of T-type Ca 2+ channels has been proposed to play a role in the therapeutic action
of succinimide antiepileptic drugs. Despite the widespread acceptance of this hypothesis, …
of succinimide antiepileptic drugs. Despite the widespread acceptance of this hypothesis, …
What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons
Electrophysiology provides a real-time readout of neural functions and network capability in
different brain states, on temporal (fractions of milliseconds) and spatial (micro, meso, and …
different brain states, on temporal (fractions of milliseconds) and spatial (micro, meso, and …
Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panel
…, P Valdes‐Sosa, M Weiergräber… - Alzheimer's & …, 2021 - Wiley Online Library
The Electrophysiology Professional Interest Area (EPIA) and Global Brain Consortium
endorsed recommendations on candidate electroencephalography (EEG) measures for …
endorsed recommendations on candidate electroencephalography (EEG) measures for …
Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice
…, C Prehn, ME Mickael, M Weiergräber… - Proceedings of the …, 2018 - National Acad Sciences
Advanced age is not only a major risk factor for a range of disorders within an aging
individual but may also enhance susceptibility for disease in the next generation. In humans, …
individual but may also enhance susceptibility for disease in the next generation. In humans, …
[HTML][HTML] Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice
…, C Schmidt-Weber, M Weiergräber… - Nature …, 2017 - nature.com
Dietary restriction regimes extend lifespan in various animal models. Here we show that
longevity in male C57BL/6J mice subjected to every-other-day feeding is associated with a …
longevity in male C57BL/6J mice subjected to every-other-day feeding is associated with a …
Disturbances in Glucose-Tolerance, Insulin-Release, and Stress-Induced Hyperglycemia upon Disruption of the Cav2.3 (α1E) Subunit of Voltage-Gated Ca2+ …
…, C Gissel, M Henry, M Weiergräber… - Molecular …, 2002 - academic.oup.com
Multiple types of voltage-activated Ca 2+ channels (T, L, N, P, Q, R type) coordinate Ca 2+ -dependent
processes in neurons and neuroendocrine cells. Expressional and functional …
processes in neurons and neuroendocrine cells. Expressional and functional …
Electrocorticographic and deep intracerebral EEG recording in mice using a telemetry system
M Weiergräber, M Henry, J Hescheler, N Smyth… - Brain research …, 2005 - Elsevier
Telemetric EEG recording plays a crucial role in the neurological characterization of various
transgenic mouse models giving valuable information about epilepsies and sleep disorders …
transgenic mouse models giving valuable information about epilepsies and sleep disorders …
[HTML][HTML] Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice
…, P Salomoni, C Schmidt-Weber, M Weiergräber… - Nature …, 2022 - nature.com
Current concepts regarding the biology of aging are primarily based on studies aimed at
identifying factors regulating lifespan. However, lifespan as a sole proxy measure for aging can …
identifying factors regulating lifespan. However, lifespan as a sole proxy measure for aging can …
[HTML][HTML] Altered theta oscillations and aberrant cortical excitatory activity in the 5XFAD model of Alzheimer's disease
…, C Wormuth, K Broich, D Ehninger, M Weiergräber… - Neural …, 2015 - hindawi.com
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder characterized by
impairment of memory function. The 5XFAD mouse model was analyzed and compared with …
impairment of memory function. The 5XFAD mouse model was analyzed and compared with …
Hippocampal Seizure Resistance and Reduced Neuronal Excitotoxicity in Mice Lacking the Cav2.3 E/R-Type Voltage-Gated Calcium Channel
M Weiergraber, M Henry… - Journal of …, 2007 - journals.physiology.org
Voltage-gated calcium channels are key components in the etiology and pathogenesis of
epilepsies. Former studies mainly focused on P/Q-type Ca v 2.1 and T-type Ca v 3.2 Ca 2+ …
epilepsies. Former studies mainly focused on P/Q-type Ca v 2.1 and T-type Ca v 3.2 Ca 2+ …