[PDF][PDF] Embryonic lethality, liver degeneration, and impaired NF-κB activation in IKK-β-deficient mice
M Tanaka, ME Fuentes, K Yamaguchi, MH Durnin… - Immunity, 1999 - cell.com
IκB kinase-α and -β (IKK-α and IKK-β), the catalytic subunits of the IKK complex, phosphorylate
IκB proteins on specific serine residues, thus targeting IκB for degradation and activating …
IκB proteins on specific serine residues, thus targeting IκB for degradation and activating …
Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1.
ME Fuentes, SK Durham, MR Swerdel… - … (Baltimore, Md.: 1950 …, 1995 - journals.aai.org
Transgenic mice overexpressing the chemokine monocyte chemoattractant protein-1 (MCP-1)
in the thymus and central nervous system have a higher number of mononuclear cells in …
in the thymus and central nervous system have a higher number of mononuclear cells in …
[HTML][HTML] In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation
…, SL Bullens, S Seeber, ME Fuentes… - The Journal of …, 2007 - Am Soc Clin Investig
Thymic stromal lymphopoietin (TSLP) potently induces deregulation of Th2 responses, a
hallmark feature of allergic inflammatory diseases such as asthma, atopic dermatitis, and …
hallmark feature of allergic inflammatory diseases such as asthma, atopic dermatitis, and …
Up-regulated expression of the CXCR2 ligand KC/GRO-α in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression
…, DM Rose, KA Johnson, ME Fuentes… - The American journal of …, 2006 - Elsevier
Macrophage-mediated inflammation is central to atherogenesis. We have determined previously
that the CXC chemokine receptor CXCR2 is involved in advanced atherosclerosis. We …
that the CXC chemokine receptor CXCR2 is involved in advanced atherosclerosis. We …
[HTML][HTML] Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis
…, Q Luo, CM Bauer, ME Fuentes… - The American journal of …, 2013 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease of high unmet medical need.
Although bromodomain (Brd) and extra terminal domain isoforms have recently been …
Although bromodomain (Brd) and extra terminal domain isoforms have recently been …
[PDF][PDF] Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes
…, TJ Brennan, K Carver-Moore, M Leviten, ME Fuentes… - Immunity, 2001 - cell.com
Lymphocytes home to lymph nodes, using L-selectin to bind specific ligands on high
endothelial venules (HEV). In vitro studies implicate GlcNAc-6-sulfate as an essential …
endothelial venules (HEV). In vitro studies implicate GlcNAc-6-sulfate as an essential …
Neutrophil infiltration, glial reaction, and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes.
M Tani, ME Fuentes, JW Peterson… - The Journal of …, 1996 - Am Soc Clin Investig
Chemokines (pro-inflammatory chemoattractant cytokines) are expressed in pathological
conditions of the central nervous system (CNS). Previous studies suggested that the CNS is …
conditions of the central nervous system (CNS). Previous studies suggested that the CNS is …
[HTML][HTML] Antibacterial defense of human airway epithelial cells from chronic obstructive pulmonary disease patients induced by acute exposure to nontypeable …
…, SR Ordonez, HP Haagsman, ME Fuentes… - Journal of innate …, 2017 - karger.com
Antimicrobial proteins and peptides (AMPs) are a central component of the antibacterial
activity of airway epithelial cells. It has been proposed that a decrease in antibacterial lung …
activity of airway epithelial cells. It has been proposed that a decrease in antibacterial lung …
BET bromodomain proteins mediate downstream signaling events following growth factor stimulation in human lung fibroblasts and are involved in bleomycin-induced …
…, S Hamilton, Z Liang, H Zeng, ME Fuentes… - Molecular …, 2013 - ASPET
Epigenetic alterations, such as histone acetylation, regulate the signaling outcomes and
phenotypic responses of fibroblasts after growth factor stimulation. The bromodomain and extra-…
phenotypic responses of fibroblasts after growth factor stimulation. The bromodomain and extra-…
Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members
…, E Agapov, TE Phillips, ME Fuentes… - Physiological …, 2006 - journals.physiology.org
Complex airway diseases such as asthma and chronic obstructive pulmonary disease exhibit
stereotyped traits (especially airway hyperreactivity and mucous cell metaplasia) that are …
stereotyped traits (especially airway hyperreactivity and mucous cell metaplasia) that are …