β 2 ‐Adrenergic and chemokine receptor antagonists delay the onset and reduce the severity
of joint injury in rheumatoid arthritis. β 2 ‐Adrenergic and chemokine receptors belong to …

Use of RNA interference to reduce huntingtin protein (htt) expression in affected brain regions
may provide an effective treatment for Huntington disease (HD), but it remains uncertain …

Many modulators of inflammation, including chemokines, neuropeptides, and
neurotransmitters signal via G protein-coupled receptors (GPCR). GPCR kinases (GRK) can …

G protein-coupled receptors (GPCR) play a crucial role in the regulation of the immune
response by, eg, chemokines, PGs, and β 2-adrenergic agonists. The responsiveness of these …

Chemokine receptors belong to the family of G-protein-coupled receptors (GPCR).
Phosphorylation of GPCR by GPCR kinases (GRKs) is considered to play an important role in …

A cDNA sequence encoding a putative peptide-specific G-protein-coupled receptor (GPR37)
was isolated from a set of human brain frontal lobe expressed sequence tags. The GPR37 …

Macrophage polarization into a phenotype producing high levels of anti-inflammatory IL-10
and low levels of proinflammatory IL-12 and TNF-α cytokines plays a pivotal role in the …

Clinical observations suggest that psychological stress induces exacerbation of disease
activity in patients with systemic lupus erythematosus (SLE). In order to determine whether SLE …

Purpose: The current study aimed to compare 2 topical diclofenac products (diclofenac
diethylamine [DEA] 1.16% emulsion and diclofenac sodium [Na] 5% gel). The quantitative …

Perinatal hypoxia ischemia (HI) is a frequent cause of neonatal brain injury. This study aimed
at describing molecular changes during the first 48 h after exposure of the neonatal rat …