User profiles for Martin J. Main
MJ MainHead of Molecular Technologies, Medicines Discovery Catapult Verified email at md.catapult.org.uk Cited by 6503 |
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
Calcitonin-gene-related peptide (CGRP) and adrenomedullin are related peptides with
distinct pharmacological profiles. Here we show that a receptor with seven transmembrane …
distinct pharmacological profiles. Here we show that a receptor with seven transmembrane …
Heterodimerization is required for the formation of a functional GABAB receptor
GABA (γ-aminobutyric acid) is the main inhibitory neurotransmitter in the mammalian central
nervous system, where it exerts its effects through ionotropic (GABA A/C ) receptors to …
nervous system, where it exerts its effects through ionotropic (GABA A/C ) receptors to …
Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product
Receptor activity-modifying proteins (RAMPs) are single-transmembrane proteins that
transport the calcitonin receptor-like receptor (CRLR) to the cell surface. RAMP 1-transported …
transport the calcitonin receptor-like receptor (CRLR) to the cell surface. RAMP 1-transported …
Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine
MJ Main, JE Cryan, JRB Dupere, B Cox, JJ Clare… - Molecular …, 2000 - ASPET
Retigabine is a novel anticonvulsant with an unknown mechanism of action. It has recently
been reported that retigabine modulates a potassium channel current in nerve growth factor-…
been reported that retigabine modulates a potassium channel current in nerve growth factor-…
Acute and late outcomes of unprotected left main stenting in comparison with surgical revascularization
…, L Rzeszutko, P Buszman, J Szymszal, JL Martin… - Journal of the American …, 2008 - jacc.org
Objectives : The purpose of this study was to compare the early and late results of
percutaneous and surgical revascularization of left main coronary artery stenosis. Background : …
percutaneous and surgical revascularization of left main coronary artery stenosis. Background : …
Biopolymer-clay nanocomposites as novel and ecofriendly adsorbents for environmental remediation
… First, the physicochemical and structural properties of clays and biopolymers as well as
the main characterization and preparation techniques are discussed. Subsequently, the main …
the main characterization and preparation techniques are discussed. Subsequently, the main …
Biogeographical patterns in the diet of an opportunistic predator: the red fox Vulpes vulpes in the Iberian Peninsula
…, JL García‐Moreno, J María López‐Martín… - Mammal …, 2013 - Wiley Online Library
… main … of main food groups in relation to geographical variables (latitude, longitude and
altitude); (ii) analysed the relationships between red fox dietary diversity, consumption of its main …
altitude); (ii) analysed the relationships between red fox dietary diversity, consumption of its main …
Ordered magnetic nanostructures: fabrication and properties
The fabrication methods and physical properties of ordered magnetic nanostructures with
dimensions on the submicron to nanometer scale are reviewed. First, various types of …
dimensions on the submicron to nanometer scale are reviewed. First, various types of …
[BOOK][B] Rapid application development
J Martin - 1991 - dl.acm.org
… This history column article provides a tour of the main software development life cycle (SDLC)
models. (A lifecycle covers all the stages of software from its inception with requirements …
models. (A lifecycle covers all the stages of software from its inception with requirements …
Energy management of a fuel cell/supercapacitor/battery power source for electric vehicular applications
… This EHPS is composed of a Fuel Cell system (FC) as the main … manage the energy between
the main and the auxiliary sources and … The main property of this strategy is that the energy …
the main and the auxiliary sources and … The main property of this strategy is that the energy …