[HTML][HTML] Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages

…, J Nelson, D Mar, K Bomsztyk, B Askari, MA Lai… - Journal of Biological …, 2013 - ASBMB
The enzyme acyl-CoA synthetase 1 (ACSL1) is induced by peroxisome proliferator-activated
receptor α (PPARα) and PPARγ in insulin target tissues, such as skeletal muscle and …

Flagellin induces antibody responses through a TLR5-and inflammasome-independent pathway

…, X Zhao, EK Quarles, MA Lai… - The Journal of …, 2014 - journals.aai.org
Flagellin is a potent immunogen that activates the innate immune system via TLR5 and
Naip5/6, and generates strong T and B cell responses. The adaptor protein MyD88 is critical for …

[HTML][HTML] Innate Immune Detection of Flagellin Positively and Negatively Regulates Salmonella Infection

MA Lai, EK Quarles, AH López-Yglesias, X Zhao… - PloS one, 2013 - journals.plos.org
Salmonella enterica serovar Typhimurium is a flagellated bacterium and one of the leading
causes of gastroenteritis in humans. Bacterial flagellin is required for motility and also a …

Ethanol reduces GABAA α1 subunit receptor surface expression by a protein kinase Cγ-dependent mechanism in cultured cerebral cortical neurons

…, KN Boyd, CE Comerford, MA Lai… - Molecular …, 2010 - ASPET
Prolonged ethanol exposure causes central nervous system hyperexcitability that involves a
loss of GABAergic inhibition. We previously demonstrated that long-term ethanol exposure …

FlgM is required to evade NLRC4-mediated host protection against flagellated Salmonella

AH López-Yglesias, CC Lu, MA Lai… - Infection and …, 2023 - Am Soc Microbiol
Salmonella enterica serovar Typhimurium is a leading cause of gastroenteritis worldwide and
a deadly pathogen in children, immunocompromised patients, and the elderly. Salmonella …

Nlrc4 inflammasome is critical for host protection against flagellated Salmonella

AH López-Yglesias, CC Lu, MA Lai, EK Quarles… - bioRxiv, 2022 - biorxiv.org
Salmonella enterica serovar Typhimurium is a leading cause of gastroenteritis worldwide and
a deadly pathogen in children, immunocompromised patients, and the elderly. Salmonella …

Commensal E. coli induced colonization resistance against mucosal Salmonella infection

C Lu, X Zhao, MA Lai, AH Lopez-Yglesias… - The Journal of …, 2016 - journals.aai.org
Salmonella is the causative agent in Salmonellosis and is a leading cause of gastrointestinal
bacterial infections worldwide. During mucosal Salmonella infection Salmonella must first …

Incidence, survival, pathology, and genetics of adult Latino Americans with glioblastoma

…, M Bergsneider, PL Nghiemphu, A Lai… - Journal of neuro …, 2017 - Springer
Latino Americans are a rapidly growing ethnic group in the United States but studies of
glioblastoma in this population are limited. We have evaluated characteristics of 21,184 …

Salmonella enterica Typhimurium evasion of caspase-1 dependent flagellin recognition promotes mucosal injury and systemic dissemination (169.4)

M Lai, E Quarles, A Lopez-Yglesias… - The Journal of …, 2012 - journals.aai.org
Salmonella enterica Typhimurium is a flagellated bacterium and one of the leading causes
of gastroenteritis in humans. Bacterial flagellin is critical for motility and also a prime target of …

[CITATION][C] Venture capitalist screening criteria and associated tools: progressive screening matrix & mean-IRR index

M Lai - iTM Ventures Inc, 2006