The endoplasmic reticulum (ER) is an essential organelle in eukaryotic cells, responsible
for protein synthesis, folding, sorting, and transportation. ER stress is initiated when the …

Cyclin-dependent kinases (CDKs) have been considered promising drug targets for a
number of years, but most CDK inhibitors have failed rigorous clinical testing. Recent studies …

Ischemia/reperfusion (I/R) injury is a causative factor contributing to morbidity and mortality
during liver resection and transplantation. Livers from elderly patients have a poorer recovery …

Tranexamic Acid (TA) is a clinically used antifibrinolytic agent that acts as a Lys mimetic to
block binding of Plasminogen with Plasminogen activators, preventing conversion of …

The 13th Acromegaly Consensus Conference was held in November 2019 in Fort
Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and …

New agents are needed that selectively kill cancer cells without harming normal tissues. The
TRAIL ligand and its receptors, DR5 and DR4, exhibit cancer-selective toxicity, but TRAIL …

Context: Transsphenoidal surgery is currently the primary therapeutic option for Cushing’s
disease. Despite considerable initial success, 10–30% of patients fail to achieve lasting …

Context: Few studies have systematically analyzed the long-term recurrence rates of Cushing’s
disease after initial successful transsphenoidal surgery. Setting: This was a retrospective …

Context: Despite the growing application of endoscopic transsphenoidal surgery (ETSS),
outcomes for GH adenomas are not clearly defined. Objective: We reviewed our experience …

Estimates of photosynthesis based on the incorporation of 14 C -labeled inorganic carbon
into particulate carbon were compared to estimates of gross photosynthesis based on net O 2 …