We identified in-frame fusion transcripts of KIF5B (the kinesin family 5B gene) and the RET
oncogene, which are present in 1–2% of lung adenocarcinomas (LADCs) from people from …

Reduction-oxidation (redox) regulation has been implicated in the activation of the transcription
factor NF-κB. However, the significance and mechanism of the redox regulation remain …

We have developed a method using novel latex beads for rapid identification of drug
receptors using affinity purification. Composed of a glycidylmethacrylate (GMA) and styrene …

Purpose: To identify druggable oncogenic fusions in invasive mucinous adenocarcinoma (IMA)
of the lung, a malignant type of lung adenocarcinoma in which KRAS mutations …

Gene activation by NF-κB/Rel transcription factors is modulated by synergistic or antagonistic
interactions with other promoter-bound transcription factors. For example, Sp1 sites are …

Netrin is a secreted protein that can act as a chemotropic axon guidance cue 1 , 2 . Two
classes of Netrin receptor, DCC 3 , 4 , 5 and UNC-5 (refs 6 , 7 , 8 , 9 ), are required for axon …

In the cell cycle, the G 1 /S transition is controlled by the cyclin‐dependent kinase (CDK) 4/6‐cyclin
D complex. Constitutive activation of CDK4/6 dysregulates G 1 /S transition, leading …

Gefitinib (GEF), an inhibitor for EGFR tyrosine kinase, potently induces autophagy in non-small
cell lung cancer (NSCLC) cell lines such as PC-9 cells expressing constitutively activated …

To determine the effects of a [6]-gingerol analogue (6G), a major chemical component of the
ginger rhizome, and its stable analogue after digestion in simulated gastric fluid, aza-[6]-…

The aim of this study was to clarify the significance of DNA methylation alterations during
non-alcoholic steatohepatitis (NASH)-related hepatocarcinogenesis. Single-CpG-resolution …