Cocaine blocks uptake by neuronal plasma membrane transporters for dopamine (DAT),
serotonin (SERT), and norepinephrine (NET). Cocaine reward/reinforcement has been linked …

Oxidative stress has become an exciting area of research on schizophrenia, which is a highly
prevalent condition that affects approximately 1% of the worldwide population. Advanced …

Compelling evidence in Caucasian populations suggests a role for copy-number variations (CNVs)
in autism spectrum disorder (ASD) and schizophrenia (SCZ). We analyzed 1,108 …

BACKGROUND: Neural endocannabinoid function appears to be involved in schizophrenia.
Two endocannabinoid receptors, CB1 and CB2, are found in the brain and elsewhere in the …

Context Various factors are involved in the pathogenesis of schizophrenia. Accumulation of
advanced glycation end products, including pentosidine, results from carbonyl stress, a state …

Appropriate biological treatment and psychosocial support are essential to achieve and
maintain recovery for patients with schizophrenia. Despite extensive efforts to clarify the …

Chromatin remodeling may play a role in the neurobiology of schizophrenia and the process,
therefore, may be considered as a therapeutic target. The SMARCA2 gene encodes BRM …

Because of a potent action of angiotensin converting enzyme (ACE) to degrade substance
P (SP) and an association of the insertion/deletion (I/D) polymorphism of the ACE gene with …

BACKGROUND: Sialyltransferase 8B (SIAT8B) and 8D (SIAT8D) are two polysialyltransferases
that catalyze the transfer of polysialic acid (PSA) to the neural cell adhesion molecule 1 (…

BACKGROUND: We previously reported a reduction in serum levels of d-serine, an endogenous
co-agonist of the N-methyl-D-aspartate (NMDA) receptor, in schizophrenia, supporting …