Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type
…, TE Monnell, MS Spaits… - Journal of applied …, 2010 - journals.physiology.org
This is the first report that inhibition of negative regulators of skeletal muscle by a soluble
form of activin type IIB receptor (ACE-031) increases muscle mass independent of fiber-type …
form of activin type IIB receptor (ACE-031) increases muscle mass independent of fiber-type …
Interferon β augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation
…, DA Goncharov, A Chisolm, MS Spaits… - Molecular …, 2008 - ASPET
Lymphangioleiomyomatosis (LAM), a rare pulmonary disorder, manifests as an abnormal
neoplastic growth of smooth muscle-like cells within the lungs. Mutational inactivation of tumor …
neoplastic growth of smooth muscle-like cells within the lungs. Mutational inactivation of tumor …
[PDF][PDF] Interferon β augments TSC2-dependent inhibition of TSC2-null ELT3 and human LAM-derived cell proliferation
…, DA Goncharov, A Chisolm, MS Spaits… - Molecular …, 2007 - Citeseer
Lymphangioleiomyomatosis (LAM), a rare pulmonary disorder, manifests as an abnormal
neoplastic growth of smooth muscle-like cells within the lungs. Mutational inactivation of tumor …
neoplastic growth of smooth muscle-like cells within the lungs. Mutational inactivation of tumor …
[PDF][PDF] Social Stress Enhances Allergen-Induced
Chronic psychosocial stress exacerbates asthma, but the underlying mechanisms remain
poorly understood. We hypothesized that psychosocial stress aggravates allergic airway …
poorly understood. We hypothesized that psychosocial stress aggravates allergic airway …
A soluble activin receptor type IIb prevents the effects of androgen deprivation on body composition and bone health
…, E Howard, J Barberio, M Spaits, S Pearsall… - …, 2010 - academic.oup.com
Androgen deprivation, a consequence of hypogonadism, certain cancer treatments, or normal
aging in men, leads to loss of muscle mass, increased adiposity, and osteoporosis. In the …
aging in men, leads to loss of muscle mass, increased adiposity, and osteoporosis. In the …
[HTML][HTML] Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension
…, TH Kuo, M Lee, E Belcheva, M Spaits… - Scientific reports, 2022 - nature.com
Sotatercept is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein that improves
cardiopulmonary function in patients with pulmonary arterial hypertension (PAH) by selectively …
cardiopulmonary function in patients with pulmonary arterial hypertension (PAH) by selectively …
Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production
MT Bailey, S Kierstein, S Sharma, M Spaits… - The journal of …, 2009 - journals.aai.org
Chronic psychosocial stress exacerbates asthma, but the underlying mechanisms remain
poorly understood. We hypothesized that psychosocial stress aggravates allergic airway …
poorly understood. We hypothesized that psychosocial stress aggravates allergic airway …
Abnormal growth of smooth muscle–like cells in lymphangioleiomyomatosis: Role for tumor suppressor TSC2
EA Goncharova, DA Goncharov, M Spaits… - American journal of …, 2006 - atsjournals.org
The TSC1 and TSC2 proteins, which function as a TSC1/TSC2 tumor suppressor complex,
are associated with lymphangioleiomyomatosis (LAM), a genetic disorder characterized by …
are associated with lymphangioleiomyomatosis (LAM), a genetic disorder characterized by …
[BOOK][B] The history and topography of the parish of Saint Mary, Islington, in the county of Middlesex
S Lewis - 1842 - books.google.com
BEING arrived at the completion of my labours, it is necessary that I should lay before the
reader such prefatory remarks, with respect to their origin and the motives with which they were …
reader such prefatory remarks, with respect to their origin and the motives with which they were …
[BOOK][B] Mid-Century Britain: Modern Architecture 1938–1963
E Harwood - 2021 - books.google.com
… It was part of a larger master plan for the arts by Charles Holden, and Robert Matthew, the
LCC’s chief architect, raised the 2,900seat concert hall – ‘the egg in the box’ – over the foyers …
LCC’s chief architect, raised the 2,900seat concert hall – ‘the egg in the box’ – over the foyers …