Hepatitis C virus (HCV) causes a persistent infection, chronic hepatitis and hepatocellular
carcinoma. HCV NS5A, one of non-structural proteins of HCV, was suggested to play a role in …

Objectives— Diabetes mellitus causes endothelial dysfunction. The precise molecular
mechanisms by which hyperglycemia causes apoptosis in endothelial cells are not yet well …

Overexpression of Her2/neu is implicated in the development of resistance to the antiestrogen
tamoxifen (TAM) that exerts its inhibitory effect through interaction with estrogen receptor (…

Diabetic myopathy, a less studied complication of diabetes, exhibits the clinical observations
characterized by a less muscle mass, muscle weakness and a reduced physical functional …

Accumulation of advanced glycation end products (AGEs) in joints is important in the development
of cartilage destruction and damage in age-related osteoarthritis (OA). The aim of this …

Purpose: Persistent interleukin-8 (IL-8) production contributes to chronic inflammation of the
stomach. The proinflammatory IL-1β polymorphisms, which enhance the cytokine production…

Peritoneal dissemination of tumor has high mortality and is associated with the loss of
epithelial features, acquisition of motile mesenchymal morphology characteristics, and invasive …

Background Honokiol, a small molecular weight natural product, has been shown to possess
potent anti-neoplastic and anti-angiogenic properties. Its molecular mechanisms and the …

Abstract Treatment of hepatocellular carcinoma (HCC) cells with butyrate can induce
apoptosis irrespective of hepatitis B virus integration. No information is available, however, …

The objective of this paper is to determine the price sensitivity of smokers in their consumption
of cigarettes, using evidence from a major increase in California cigarette prices due to …