The metabolic syndrome is a common precursor of cardiovascular disease and type 2 diabetes
that is characterized by the clustering of insulin resistance, dyslipidemia, and increased …

A 10-step stereoselective total synthesis of the antimalarial cadinanesesquiterpene (+)-artemisinin
(1) is described. Elaboration of (/?)-(+)-pulegone to the known sulfoxide 11 was …

Artemisinin drugs are of utmost importance in the treatment of malaria, because they represent
the sole class of therapeutically used antimalarial drugs to which malaria parasites have …

The objective of the present research was to evaluate the physicochemical characteristics of
berberine chloride and to assess the complexation of drug with 2-hydroxypropyl-β-…

Type II diabetes is a heterogeneous disease where environment and genetics are important
factors for the expression of the disease. The high cost for treating complications of diabetes …

The 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway for isoprenoid biosynthesis has
come under increased scrutiny as a target for novel antimalarial, antibacterial and herbicidal …

The rare indazole-type alkaloid nigellidine (2) is accompanied by its 4-O-sulfite (4) in the
seeds of Nigella sativa. Compound 4 may represent the true natural product leading to …

Artemisinin (1) and its analogues have been well studied for their antimalarial activity. Here
we present the antimalarial activity of some novel C-9-modified artemisinin analogues …

Giardiasis is a protozoal disease infecting 200 million people throughout the world.
Giardiasis is widespread primarily in developing countries. Infections are correlated with poor …

This review covers developments in relation to artemisinin-based antimalarial agents.
Topics covered include a brief introduction to the history and treatment of malaria, and more …