[HTML][HTML] TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fibrosis in murine full-thickness skin …
…, A Sindrilaru, A Stegemann, S Schatz, N Treiber… - Journal of Investigative …, 2014 - Elsevier
Proper activation of macrophages (Mφ) in the inflammatory phase of acute wound healing is
essential for physiological tissue repair. However, there is a strong indication that robust Mφ …
essential for physiological tissue repair. However, there is a strong indication that robust Mφ …
Molecular mechanisms of the crosstalk between mitochondria and NADPH oxidase through reactive oxygen species—studies in white blood cells and in animal …
…, E Zinßius, M Mader, P Stamm, N Treiber… - Antioxidants & redox …, 2014 - liebertpub.com
Aims: Oxidative stress is involved in the development of cardiovascular disease. There is a
growing body of evidence for a crosstalk between different enzymatic sources of oxidative …
growing body of evidence for a crosstalk between different enzymatic sources of oxidative …
Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular …
…, M Oelze, E Schulz, N Treiber… - Cardiovascular …, 2008 - academic.oup.com
Aims Imbalance between pro- and antioxidant species (eg during aging) plays a crucial role
for vascular function and is associated with oxidative gene regulation and modification. …
for vascular function and is associated with oxidative gene regulation and modification. …
Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue
N Treiber, P Maity, K Singh, M Kohn, AF Keist… - Aging cell, 2011 - Wiley Online Library
The free radical theory of aging postulates that the production of mitochondrial reactive oxygen
species is the major determinant of aging and lifespan. Its role in aging of the connective …
species is the major determinant of aging and lifespan. Its role in aging of the connective …
The role of manganese superoxide dismutase in skin aging
N Treiber, P Maity, K Singh, F Ferchiu… - Dermato …, 2012 - Taylor & Francis
The free radical theory of aging postulates that the production of mitochondrial reactive oxygen
species is the major determinant of aging and lifespan. The skin represents an excellent …
species is the major determinant of aging and lifespan. The skin represents an excellent …
Heterozygous deficiency of manganese superoxide dismutase in mice (Mn-SOD+/-): a novel approach to assess the role of oxidative stress for the development of …
…, S Sulyok, M Coldewey, E Schulz, N Treiber… - Molecular …, 2005 - ASPET
Nitroglycerin (GTN)-induced tolerance was reported to be associated with increased levels
of reactive oxygen species (ROS) in mitochondria. In the present study, we further …
of reactive oxygen species (ROS) in mitochondria. In the present study, we further …
[HTML][HTML] Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration
V Farsam, A Basu, M Gatzka, N Treiber, LA Schneider… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Aging is associated with a rising incidence of cutaneous squamous cell carcinoma (cSCC),
an aggressive skin cancer with the potential for local invasion and metastasis. Acquisition of …
an aggressive skin cancer with the potential for local invasion and metastasis. Acquisition of …
Downregulation of c-Jun expression by transcription factor C/EBPα is critical for granulocytic lineage commitment
J Rangatia, RK Vangala, N Treiber… - … and cellular biology, 2002 - Taylor & Francis
The transcription factor C/EBPα is crucial for the differentiation of granulocytes. Conditional
expression of C/EBPα triggers neutrophilic differentiation, and C/EBPα can block 12-O-…
expression of C/EBPα triggers neutrophilic differentiation, and C/EBPα can block 12-O-…
[HTML][HTML] A novel S100A8/A9 induced fingerprint of mesenchymal stem cells associated with enhanced wound healing
…, K Singh, D Crisan, A Sindrilaru, N Treiber… - Scientific reports, 2018 - nature.com
We here investigated whether the unique capacity of mesenchymal stem cells (MSCs) to re-establish
tissue homeostasis depends on their potential to sense danger associated …
tissue homeostasis depends on their potential to sense danger associated …
Superoxide anion radicals induce IGF‐1 resistance through concomitant activation of PTP 1 B and PTEN
K Singh, P Maity, L Krug, P Meyer, N Treiber… - EMBO molecular …, 2015 - embopress.org
The evolutionarily conserved IGF ‐1 signalling pathway is associated with longevity,
metabolism, tissue homeostasis, and cancer progression. Its regulation relies on the delicate …
metabolism, tissue homeostasis, and cancer progression. Its regulation relies on the delicate …