Isolation and expression of a novel angiotensin II receptor from Xenopus laevis heart.
DJ Bergsma, C Ellis, PR Nuthulaganti, P Nambi… - Molecular …, 1993 - ASPET
A Xenopus laevis heart cDNA library was screened using the human angiotensin type 1 (AT1)
receptor cDNA coding sequence as a hybridization probe. A cDNA was isolated that …
receptor cDNA coding sequence as a hybridization probe. A cDNA was isolated that …
Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor
…, W Halsey, G Sathe, AI Muir, P Nuthulaganti… - Molecular …, 1999 - ASPET
The cysteinyl leukotrienes (CysLTs) have been implicated in the pathophysiology of inflammatory
disorders, in particular asthma, for which the CysLT receptor antagonists pranlukast, …
disorders, in particular asthma, for which the CysLT receptor antagonists pranlukast, …
[HTML][HTML] Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor
…, DA Groarke, KB Tan, U Shabon, P Nuthulaganti… - Journal of Biological …, 2000 - ASBMB
Opiate tolerance and dependence are major clinical and social problems. The anti-opiate
neuropeptides FF and AF (NPFF and NPAF) have been implicated in pain modulation as well …
neuropeptides FF and AF (NPFF and NPAF) have been implicated in pain modulation as well …
[PDF][PDF] Another Way to Break Hearts: Reverse Takotsubo Cardiomyopathy
Y Zhang, SR Nuthulaganti, K Liu, A Blanco, K Esmail - Cureus, 2022 - cureus.com
… Electrocardiogram revealed sinus tachycardia and PR interval shortening with
nonspecific T-wave changes. The patient was taken for cardiac catheterization, revealing …
nonspecific T-wave changes. The patient was taken for cardiac catheterization, revealing …
[PDF][PDF] Blasting Into Acute Coronary Syndrome
SR Nuthulaganti, F Kandah, ME Valentin, M Gutierrez… - Cureus, 2021 - cureus.com
Acute coronary syndrome (ACS) is a condition that develops from reduced blood flow and
oxygen delivery through the coronary arteries which leads to cardiac ischemia. In the case …
oxygen delivery through the coronary arteries which leads to cardiac ischemia. In the case …
BacMam recombinant baculoviruses in G protein–coupled receptor drug discovery
RS Ames, JA Fornwald, P Nuthulaganti… - Receptors and …, 2004 - Taylor & Francis
With completion of the sequencing of the human and mouse genomes, the primary
sequences of close to 400 non-olfactory G protein–coupled receptors (GPCRs) have been …
sequences of close to 400 non-olfactory G protein–coupled receptors (GPCRs) have been …
M3 muscarinic acetylcholine receptor antagonists: SAR and optimization of bi-aryl amines
…, H Xie, Z Wan, C Zhu, JJ Foley, P Nuthulaganti… - Bioorganic & medicinal …, 2009 - Elsevier
Exploration of multiple regions of a bi-aryl amine template led to the identification of highly
potent M 3 muscarinic acetylcholine receptor antagonists such as 14 (pA 2 =11.0) possessing …
potent M 3 muscarinic acetylcholine receptor antagonists such as 14 (pA 2 =11.0) possessing …
[HTML][HTML] Neuropeptide AF and FF modulation of adipocyte metabolism: primary insights from functional genomics and effects on β-adrenergic responsiveness
I Lefrere, P De Coppet, JC Camelin, S Le Lay… - Journal of Biological …, 2002 - ASBMB
The presence of a neuropeptide AF and FF receptor (NPFF-R2) mRNA in human adipose
tissue (Elshourbagy, NA, Ames, RS, Fitzgerald, LR, Foley, JJ, Chambers, JK, Szekeres, PG, …
tissue (Elshourbagy, NA, Ames, RS, Fitzgerald, LR, Foley, JJ, Chambers, JK, Szekeres, PG, …
[HTML][HTML] Mutagenesis and the Molecular Modeling of the Rat Angiotensin II Receptor (AT1)∗
Y Yamano, K Ohyama, M Kikyo, T Sano… - Journal of Biological …, 1995 - ASBMB
The molecular interaction involved in the ligand binding of the rat angiotensin II receptor (AT
1A ) was studied by site-directed mutagenesis and receptor model building. The three-…
1A ) was studied by site-directed mutagenesis and receptor model building. The three-…
[HTML][HTML] Non-peptide Angiotensin Agonist: FUNCTIONAL AND MOLECULAR INTERACTION WITH THE AT1 RECEPTOR (∗)
S Perlman, HT Schambye, RA Rivero… - Journal of Biological …, 1995 - ASBMB
Non-peptide ligands for peptide receptors of the G-protein-coupled type are generally
antagonists, except in the opiate system. Recently, it was observed that a subset of …
antagonists, except in the opiate system. Recently, it was observed that a subset of …