Sarcoplasmic reticulum Ca2+-pump dysfunction in rat cardiomyocytes briefly exposed to hydoxyl radicals

TE Morris, PV Sulakhe - Free Radical Biology and Medicine, 1997 - Elsevier
The effects of hydroxyl radical exposure of intact cardiomyocytes on sarcoplasmic reticulum (SR)
function were investigated. For this purpose, isolated rat heart myocytes were exposed …

Regulation of phospholamban and troponin-I phosphorylation in the intact rat cardiomyocytes by adrenergic and cholinergic stimuli: roles of cyclic nucleotides …

PV Sulakhe, XT Vo - Signal Transduction Mechanisms, 1995 - Springer
Protein phosphorylation was investigated in [ 32 P]-labeled cardiomyocytes isolated from
adult rat heart ventricles. The β-adrenergic stimulation (by isoproterenol, ISO) increased the …

Adenylate cyclase in skeletal muscle: kinetic properties and hormonal stimulation

DL Severson, GI Drummond, PV Sulakhe - Journal of Biological Chemistry, 1972 - Elsevier
Adenylate cyclase was studied in plasma membranes prepared from rabbit skeletal muscle.
Such preparations represented an increase in specific activity of 10- to 20-fold over the …

Excitation-contraction coupling in heart: VII. Calcium accumulation in subcellular particles in congestive heart failure

PV Sulakhe, NS Dhalla - The Journal of Clinical …, 1971 - Am Soc Clin Investig
The ability of heavy microsomes and mitochondria, isolated from the control and failing hearts
of genetically dystrophic hamsters (BIO 14.6 strain), to accumulate calcium was examined. …

The release of 3H-adenosine and its derivatives from cat sensorimotor cortex

PV Sulakhe, JW Phillis - Life sciences, 1975 - Elsevier
The release of tritiated adenosine and its derivatives from the surface of the pericruciate
sensorimotor cortex of cats has been measured. Most of the radioactive material was released …

Requirement for sulfhydryl groups in the differential effects of magnesium ion and GTP on agonist binding of muscarinic cholinergic receptor sites in rat atrial …

JW Wei, PV Sulakhe - Naunyn-Schmiedeberg's archives of pharmacology, 1980 - Springer
… In agreement with the previous observations from this laboratory (Wei and Sulakhe, 1979a,
b; 1980), the present study shows that in the case of rat heart atrial muscarinic receptor sites, (…

Regional and subcellular distribution of myocardial muscarinic cholinergic receptors

JW Wei, PV Sulakhe - European journal of pharmacology, 1978 - Elsevier
Regional and subcellular distribution of muscarinic cholinergic receptors were investigated
in the myocardium of commonly used laboratory animals. The density of receptor sites (…

Isolation of skeletal muscle membrane fragments containing active Na+ K+ stimulated ATPase: Comparison of normal and dystrophic muscle sarcolemma

PV Sulakhe, M Fedelesova, DB McNamara… - Biochemical and …, 1971 - Elsevier
A method for the isolation of skeletal muscle membrane is described. These membrane
fragments were found to contain a highly active Na + K + stimulated Mg ++ dependent ATPase …

Calcium binding by skeletal muscle sarcolemma

PV Sulakhe, GI Drummond, DC Ng - Journal of Biological Chemistry, 1973 - Elsevier
Plasma membranes isolated from rabbit muscle possessed the ability to bind and accumulate
calcium ions; these processes required ATP and Mg 2+ . Binding of Ca 2+ was rapid, …

Properties of heart sarcolemmal Na+-K+ ATPase

DB McNAMARA, PV SULAKHE, JN SINGH… - The Journal of …, 1974 - jstage.jst.go.jp
MATERIALS AND METHODS Mongrel dogs(10-15kg) were anesthesized with 30mg/kg
sodium pentobarbitol(intrave nously). The hearts were rapidly removed and placed in ice cold …