It is likely that the environment within the injured spinal cord influences the capacity of fetal
spinal cord transplants to support axonal growth. We have recently demonstrated that fetal …

Activation of T cells via the stimulation of the TCR plays a central role in the adaptive
immunological response. Although much is known about TCR-stimulated signaling pathways, there …

The Tec family kinase Itk is an important regulator of Ca 2+ mobilization and is required for
in vivo responses to Th2-inducing agents. Recent data also implicate Itk in TCR-induced …

Epibatidine is an alkaloid that was first isolated from the skin of the Ecuadoran frog Epipedobates
tricolor by Daly et al.[J. Am. Chem. Soc. 102: 803-836(1 980)] and was found to have …

The Tec family non‐receptor tyrosine kinases have been recognized for their roles in the
regulation of phospholipase C‐γ and Ca 2+ mobilization downstream from antigen receptors on …

Several studies have demonstrated that opioids regulate a number of immune cell functions
either through direct mechanisms or through the modulation of central nervous system …

Previous reports have shown that the LEW/N and F344/N inbred rat strains display a
differential sensitivity to cocaine in a number of preparations, with the LEW/N rats displaying an …

Administration of morphine (10 mg/kg) to rats was found to decrease the proliferative potential
of blood lymphocytes by 60‐80% and concurrently elevate circulating levels of the cytokine…

Morphine has been shown to alter gene expression of the major histocompatibility complex,
class II (MHC-II) in circulating rat immunocytes. Here, we demonstrate that a single …

We have characterized high affinity neuronal nicotinic acetylcholine receptors labeled by [ 3
H ]cytisine in primary neuronal cell cultures from fetal rat brains. After 15 days in culture, the …