Alzheimer's disease (AD) is a neurodegenerative disorder of the brain characterized by the
presence of neuritic amyloid plaques and neurofibrillary tangles. Although it most frequently …

… McPhie and RL Neve, unpublished data). Thus, co-infection with HSV vectors is an efficient
way to obtain expression of multiple gene products within individual primary culture neurons. …

While stressful life events are an important cause of psychopathology, most individuals
exposed to adversity maintain normal psychological functioning. The molecular mechanisms …

The amyloid β protein has been identified as an important component of both
cerebrovascular amyloid and amyloid plaques of Alzheimer's disease and Down syndrome. A …

To better understand the molecular mechanisms of depression and antidepressant action,
we administered chronic social defeat stress followed by chronic imipramine (a tricyclic …

CYTOGENETIC analysis has identified chromosome Ilpl3 as the smallest overlap region for
deletions found in individuals with WAGR syndrome, which includes Wilms tumour (a …

Duchenne muscular dystrophy (DMD) and the less severe Becker muscular dystrophy (BMD)
are human X-linked muscle-wasting disorders that have been localized to the band Xp21 …

The inhibitory activity associated with myelin is a major obstacle for successful axon
regeneration in the adult mammalian central nervous system (CNS) 1 , 2 . In addition to myelin-…

Amyloid B-protein/amyloid A4 is a peptide present in the neuritic plaques, neurofibrillary
tangles and cerebrovascular deposits in patients with Alzheimer's disease and Down's …

Cocaine regulates the transcription factor CREB (adenosine 3′,5′-monophosphate response
element binding protein) in rat nucleus accumbens, a brain region that is important for …