Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide,
but credible estimates from the World Health Organization and the International Agency for …

Loss of RB1 gene is considered either a causal or an accelerating event in retinoblastoma.
A variety of mechanisms inactivates RB1 gene, including intragenic mutations, loss of …

In the last decades the approach to cancer patient management has been deeply revolutionized.
We are moving from a “one-fits-all” strategy to the “personalized medicine” based on …

Triple-negative breast cancers (TNBCs) are clinically aggressive forms associated with a
poor prognosis. We evaluated the cytotoxic effect exerted on triple-negative MDA-MB231 …

Cancer stem cells (CSC) have a central role in driving tumor growth. Since metabolism is
becoming an important diagnostic and therapeutic target, characterization of CSC line …

Triple-negative breast cancers (TNBCs) are aggressive forms of breast carcinoma associated
with a high rate of recidivism. In this paper, we report the production of mammospheres …

This article shows that HepG2, Hep3B, and SK‐Hep1 cells, three lines of human hepatocellular
carcinoma (HCC) cells, are resistant to apoptosis induced by tumor necrosis factor‐…

A novel cancer stem‐like cell line (3AB‐OS), expressing a number of pluripotent stem cell
markers, was irreversibly selected from human osteosarcoma MG‐63 cells by long‐term …

The proteasome inhibitor bortezomib is an efficacious apoptotic agent in many tumor cells.
This paper shows that bortezomib induced apoptosis in human hepatoma HepG2 cells …

As part of the Halifax Project, this review brings attention to the potential effects of environmental
chemicals on important molecular and cellular regulators of the cancer hallmark of …