Role of the development scientist in compound lead selection and optimization

S Venkatesh, RA Lipper - Journal of pharmaceutical sciences, 2000 - Elsevier
The R&D process for bringing drugs from discovery laboratories to the marketplace is
undergoing rapid change, as enabled by new technologies and as demanded by the global …

Summary workshop report: biopharmaceutics classification system—implementation challenges and extension opportunities

…, G Kwei, VHL Lee, LJ Lesko, RA Lipper… - Journal of …, 2004 - jpharmsci.org
JAMES E. POLLI, 1 LAWRENCE X. YU, 2 JACK A. COOK, 3 GORDON L. AMIDON, 4 RONALD
T. BORCHARDT, 5 BETH A. BURNSIDE, 6 PHILIP S. BURTON, 7 MEI-LING CHEN, 2 …

Summary workshop report: bioequivalence, biopharmaceutics classification system, and beyond

…, P Fackler, K Hartauer, G Johnston, SL Krill, RA Lipper… - The AAPS journal, 2008 - Springer
The workshop “Bioequivalence, Biopharmaceutics Classification System, and Beyond” was
held May 21–23, 2007 in North Bethesda, MD, USA. This workshop provided an opportunity …

In Vivo Evaluation of the Absorption and Gastrointestinal Transit of Avitriptan in Fed and Fasted Subjects Using Gamma Scintigraphy

…, DS Greene, RH Barbhaiya, RA Lipper… - … of pharmacokinetics and …, 1998 - Springer
The study was conducted to assess the bioavailability of avitriptan after a standard high fat
meal, in relation to gastrointestinal transit. Six healthy male subjects were enrolled in a four-…

Introduction to biopharmaceutics and its role in drug development

NP Barbour, RA Lipper - Biopharmaceutics Applications in Drug …, 2008 - Springer
In the world of drug development, the meaning of the term “biopharmaceutics” often evokes
confusion, even among scientists and professionals who work in the field. “Pharmaceutics” …

[PDF][PDF] Inhibition of Drug Metabolism by a Prodrug: 9-β-D-Arabinofuranosyladenine 5'-Valerate as an Inhibitor of Adenosine Deaminase

RA Lipper, SM Machkovech, JC Drach… - Molecular …, 1978 - Citeseer
Inhibition of Drug Metabolism by a Prodrug: Arabinofuranosyladenine 5’-Valerate as an
Inhibitor of Adenosine Deami nase Page 1 MOLECULAR PHARMACOLOGY, 14, 366-369 …

Degradation kinetics and mechanism of N6-[(dimethylamino) methylene] mitomycin C in aqueous solutions

…, WH Johns, JB Bogardus, RA Lipper - Journal of …, 1986 - Elsevier
The degradation of N 6 -[(dimethylamino)methylene]mitomycin C, a semisynthetic analogue
of mitomycin C, was studied in aqueous solution. The compound degraded rapidly and …

[BOOK][B] Prodrug Approach To Intracellular Drug Delivery: A Comparative Evaluation Of Vidarabine And Vidarabine-5'-valerate In Mammalian Cell Cultures.

RA Lipper - 1978 - search.proquest.com
In recent years, optimization of the drug delivery process has been a popular and fruitful
domain for research in the pharmaceutical sciences. As was illustrated by the tongue-in-cheek …

AAPS Advances in the Pharmaceutical Sciences Series

DJA Crommelin, RA Lipper - Springer
The AAPS Advances in the Pharmaceutical Sciences Series, published in partnership with
the American Association of Pharmaceutical Scientists, is designed to deliver well written …

[HTML][HTML] Sustainable intensification: What is its role in climate smart agriculture?

…, P Thornton, R Zougmoré, P Van Asten, L Lipper - Current Opinion in …, 2014 - Elsevier
Highlights • ‘Sustainable intensification’(SI) and ‘climate-smart agriculture’(CSA) are closely
interlinked. • The main difference is the focus in CSA on outcomes related to climate change …