Background Narcolepsy results from immune-mediated destruction of hypocretin secreting
neurons in hypothalamus, however the triggers and disease mechanisms are poorly …

Although patients with chronic renal failure are increasing worldwide, many aspects of
kidney biology remain to be elucidated. Recent research has uncovered several molecular …

Temporin A (TA) is a small, basic, highly hydrophobic, antimicrobial peptide amide (FLPLIGRVLSGIL‐NH
2 ) found in the skin of the European red frog, Rana temporaria. It has variable …

Background Considerable interest in the bioconversion of lignocellulosic biomass into ethanol
has led to metabolic engineering of Saccharomyces cerevisiae for fermentation of xylose. …

Western-style diets (WD) high in fat and scarce in fiber and vitamin D increase risks of colorectal
cancer. Here, we performed a long-term diet study in mice to follow tumorigenesis and …

SETBP1 variants occur as somatic mutations in several hematological malignancies such
as atypical chronic myeloid leukemia and as de novo germline mutations in the Schinzel–…

Lipid accumulation is a key characteristic of advancing atherosclerotic lesions. Herein, we
analyzed the ultrastructure of the accumulated lipids in endarterectomized human carotid …

LACTB is a mammalian active-site serine protein that has evolved from a bacterial penicillin-binding
protein. Penicillin-binding proteins are involved in the metabolism of peptidoglycan, …

Female middle age is characterized by a decline in skeletal muscle mass and performance,
predisposing women to sarcopenia, functional limitations, and metabolic dysfunction as they …

Hantaviruses cause two severe diseases, haemorrhagic fever with renal syndrome in
Eurasia and hantavirus pulmonary syndrome in the Americas. To understand more about the …