User profiles for Rae-Kwon Kim

Rae-Kwon Kim

Korea Atomic Energy Research Institute
Verified email at kaeri.re.kr
Cited by 1925

[HTML][HTML] Clogging-free microfluidics for continuous size-based separation of microparticles

Y Yoon, S Kim, J Lee, J Choi, RK Kim, SJ Lee, O Sul… - Scientific reports, 2016 - nature.com
In microfluidic filtration systems, one of the leading obstacles to efficient, continuous
operation is clogging of the filters. Here, we introduce a lateral flow microfluidic sieving (μ-sieving) …

[HTML][HTML] PTTG1 oncogene promotes tumor malignancy via epithelial to mesenchymal transition and expansion of cancer stem cell population

CH Yoon, MJ Kim, H Lee, RK Kim, EJ Lim… - Journal of Biological …, 2012 - ASBMB
The prognosis of breast cancer patients is related to the degree of metastasis. However, the
mechanisms by which epithelial tumor cells escape from the primary tumor and colonize at a …

[HTML][HTML] Activation of KRAS promotes the mesenchymal features of basal-type breast cancer

…, KC Yoo, YH Cui, H Kim, MJ Kim, I Gyu Kim… - … & molecular medicine, 2015 - nature.com
Basal-type breast cancers are among the most aggressive and deadly breast cancer subtypes,
displaying a high metastatic ability associated with mesenchymal features. However, the …

[HTML][HTML] Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer

RK Kim, N Kaushik, Y Suh, KC Yoo, YH Cui, MJ Kim… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Epithelial to mesenchymal transition (EMT) is developmental process associated with
cancer metastasis. Here, we found that breast carcinoma cells adopt epithelial-to-mesenchymal …

Phloroglucinol suppresses metastatic ability of breast cancer cells by inhibition of epithelial‐mesenchymal cell transition

…, YH Cui, E Hwang, HJ Kim, JS Kang, MJ Kim… - Cancer …, 2015 - Wiley Online Library
Metastasis is a challenging clinical problem and the primary cause of death in breast cancer
patients. However, there is no therapeutic agent against metastasis of breast cancer cells. …

Crosstalk between GBM cells and mesenchymal stemlike cells promotes the invasiveness of GBM through the C5a/p38/ZEB1 axis

…, MJ Kim, MJ Park, RK Kim, J Cha, SH Kim… - Neuro …, 2020 - academic.oup.com
Background Mesenchymal stemlike cells (MSLCs) have been detected in many types of
cancer including brain tumors and have received attention as stromal cells in the tumor …

Titanium dioxide induces apoptotic cell death through reactive oxygen species-mediated Fas upregulation and Bax activation

…, SJ Woo, RK Kim, EJ Lim, Y Suh, MJ Kim… - International journal …, 2012 - Taylor & Francis
Background Titanium dioxide (TiO 2 ) has been widely used in many areas, including
biomedicine, cosmetics, and environmental engineering. Recently, it has become evident that …

[HTML][HTML] Tescalcin/c-Src/IGF1Rβ-mediated STAT3 activation enhances cancer stemness and radioresistant properties through ALDH1

JH Lee, SI Choi, RK Kim, EW Cho, IG Kim - Scientific reports, 2018 - nature.com
Tescalcin (TESC; also known as calcineurin B homologous protein 3, CHP3) has recently
reported as a regulator of cancer progression. Here, we showed that the elevation of TESC in …

[HTML][HTML] Doxycycline enhances survival and self-renewal of human pluripotent stem cells

MY Chang, YH Rhee, SH Yi, SJ Lee, RK Kim, H Kim… - Stem cell reports, 2014 - cell.com
We here report that doxycycline, an antibacterial agent, exerts dramatic effects on human
embryonic stem and induced pluripotent stem cells (hESC/iPSCs) survival and self-renewal. …

Persistent activation of STAT 3 by PIM 2‐driven positive feedback loop for epithelial‐mesenchymal transition in breast cancer

…, RK Kim, KC Yoo, YH Kim, YH Cui, IG Kim… - Cancer …, 2015 - Wiley Online Library
Metastasis of breast cancer is promoted by epithelial–mesenchymal transition ( EMT ).
Emerging evidence suggests that STAT 3 is a critical signaling node in EMT and is constitutively …