User profiles for Ranjit Desai

Ranjit R DESAI

National Renewable Energy Laboratory
Verified email at nrel.gov
Cited by 97

Prolyl hydroxylase inhibitors: a breakthrough in the therapy of anemia associated with chronic diseases

…, VB Pandya, VJ Patel, RC Desai… - Journal of medicinal …, 2018 - ACS Publications
Chronic kidney disease, cancer, chronic inflammatory disorders, nutritional, and genetic
deficiency can cause anemia. Hypoxia causes induction of hypoxia-inducible factor (HIF), which …

Combating autoimmune diseases with retinoic acid receptor-related orphan receptor-γ (RORγ or RORc) inhibitors: hits and misses

…, Sachchidanand, R Sharma, RC Desai - Journal of medicinal …, 2018 - ACS Publications
The nuclear receptor retinoic acid receptor-related orphan receptor gamma (RORγ or RORc)
is a key transcription factor for the production of pro-inflammatory cytokines implicated in …

[HTML][HTML] Interaction of consumer heterogeneity and technological progress in the US electric vehicle market

RR Desai, E Hittinger, E Williams - Energies, 2022 - mdpi.com
Electric Technology Vehicles (ETVs: hybrid, electric, and plug-in hybrid) may reach price parity
with incumbent internal combustion vehicles (ICEVs) in the near future. Climate policy for …

Heterogeneity in economic and carbon benefits of electric technology vehicles in the US

RR Desai, RB Chen, E Hittinger… - Environmental science & …, 2019 - ACS Publications
To broadly contribute to sustainable mobility, electric technology vehicles (hybrid, electric,
and plug-in-hybrid) must become more price competitive with internal combustion vehicles. …

5-Aryl thiazolidine-2, 4-diones: discovery of PPAR dual α/γ agonists as antidiabetic agents

RC Desai, W Han, EJ Metzger, JP Bergman… - Bioorganic & Medicinal …, 2003 - Elsevier
A novel series of 5-aryl thiazolidine-2,4-diones based dual PPARα/γ agonists was identified.
A number of highly potent and orally bioavailable analogues were synthesized. Efficacy …

[HTML][HTML] A pattern analysis of daily electric vehicle charging profiles: Operational efficiency and environmental impacts

RR Desai, RB Chen, W Armington - Journal of Advanced …, 2018 - hindawi.com
Plug-in Electric Vehicles (PEVs) are considered one solution to reducing GHG emissions
from private transport. Additionally, PEV adopters often have free access to public charging …

Discovery of a potent and orally efficacious TGR5 receptor agonist

…, P Giri, H Patel, S Giri, M Jain, RC Desai - ACS medicinal …, 2016 - ACS Publications
TGR5 is a G protein-coupled receptor (GPCR), activation of which promotes secretion of
glucagon-like peptide-1 (GLP-1) and modulates insulin secretion. The 2-thio-imidazole …

(2R)-2-Ethylchromane-2-carboxylic Acids:  Discovery of Novel PPARα/γ Dual Agonists as Antihyperglycemic and Hypolipidemic Agents

…, DJ Miller, JK Boueres, RC Desai… - Journal of medicinal …, 2004 - ACS Publications
A series of chromane-2-carboxylic acid derivatives was synthesized and evaluated for PPAR
agonist activities. A structure−activity relationship was developed toward PPARα/γ dual …

ZYKR1, a novel, potent, and peripherally selective kappa opioid receptor agonist reduces visceral pain and pruritus in animal models

…, HM Kawade, DM Kokare, V Pawar, R Desai - European Journal of …, 2022 - Elsevier
Opioid receptor agonists are effective analgesic agents. Central activation of the mu and/or
kappa opioid receptors (KOR) is associated with CNS side effects, which limits their …

CONIVAS: CONtent-based image and video access system

M Abdel-Mottaleb, N Dimitrova, R Desai… - Proceedings of the fourth …, 1997 - dl.acm.org
We have developed a CO Ntent-based Image and Video Access System(CO NIVAS). The
system consists of a collection of tools to help users retrieve still images and videos from …