Cytotoxic T lymphocytes (CTLs) control viral infections by recognizing viral peptides presented
by major histocompatibility complex (MHC) class I molecules. Human leukocyte antigen (…

OBJECTIVES: Multiple sclerosis (MS) is a chronic inflammatory response against constituents
of the central nervous system. It is known that regulatory T cells (Tregs) play a key role in …

Proteasome inhibitors have potential for the treatment of cervical cancer. We describe the
synthesis and biological characterization of a new series of 1,3-diphenylpropen-1-one (…

Tat, the trans activation protein of HIV, is produced early upon infection to promote and
expand HIV replication and transmission. However, Tat appears to also have effects on target …

The present study investigates mRNA and protein levels of A 3 adenosine receptors in resting
(R) and activated (A) human lymphocytes. The receptors were evaluated by the antagonist …

The majority of hepatitis C virus (HCV)‐infected individuals fail to resolve the infection and
become chronically infected despite the presence of HCV‐specific CTL responses directed to …

Advanced age is associated with severe symptoms and death upon SARS-CoV-2 infection.
Virus-specific CD8 + T-cell responses have shown to be protective toward critical COVID-19 …

The T cell receptor (TCR) repertoires of cytotoxic responses to the immunodominant and
subdominant HLA A11–restricted epitopes in the Epstein-Barr virus (EBV) nuclear antigen-4 …

Novel biocompatible core-shell cationic nanoparticles, composed of an inner hard core of
poly(methylmethacrylate) (PMMA) and a hydrophilic tentacular shell bearing positively …

We have previously shown that the biologically active Tat protein targets and efficiently enters
dendritic cells, and increases the proteolytic activities of the immunoproteasome, thereby …