β-Adrenergic receptor blockers (β-blockers) are commonly used to treat heart failure, but the
biologic mechanisms governing their efficacy are still poorly understood. The complexity of β…

Cardiovascular diseases are among the leading causes of death in the developed world.
Developing novel therapies for diseases like heart failure is crucial, but this is hampered by the …

Using eight newly generated models relevant to addiction, Alzheimer’s disease, cancer,
diabetes, HIV, heart disease, malaria, and tuberculosis, we show that systems analysis of small (…

Intracellular Ca 2+ dynamics act as a key link between the electrical and mechanical activity
of the heart. Here we present a method for high-throughput measurement, automated cell …

… The text of Chapter 2, in part, is a partial reprint of material as it appears in Amanfu, RK & …
The text of Chapter 3 is a reprint of material as it appears in Amanfu, RK, Muller, JB & …

The scientific community is divided in support of two major hypotheses of the controversial
etiology of the Transmissible Spongiform Encephalopathy (TSE) variant Creutzfeldt-Jakob …

Muller and co-workers were the first to report the synthesis of a symmetric bicyclic analogue
of ferroene, by treating the anion of bicyclo (3.2. 2) nona-2, 6, 8-triene (BCNT) with ferrous …

Objectives. To describe trends and category of disabilities caused by Buruli ulcer disease.
Design. This retrospective study was set up to quantify information on the disability trends …

The purpose of this dissertation was to explore governance issues in contemporary Africa,
focusing specifically on Ghana's recent political transformations. It is one of the recent studies …

Archaeological evidence is not the first source of data that one would consider informative
when it comes to investigating tuberculosis in modern populations. However, technological …