Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships

RO Beleboni, ROG Carolino, AB Pizzo… - Cellular and molecular …, 2004 - Springer
… Renê Oliveira Beleboni … Ruither Oliveira Gomes Carolino … Agostinho, P., Duarte, CB,
Carvalho, AP, and Oliveira, CR (1994). Effect of oxidative stress on the release of [ 3 H]GABA in …

Effects of prolonged neuronal nitric oxide synthase inhibition on the development and expression of L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats

…, R Cavalcanti-Kiwiatkoviski, ROG Carolino… - …, 2015 - Elsevier
It is well known that nitric oxide (NO) interacts with dopamine (DA) within the striatal circuitry.
The anti-dyskinetic properties of NO synthase (NOS) inhibitors demonstrate the importance …

Persistent inflammatory pain is linked with anxiety-like behaviors, increased blood corticosterone, and reduced global DNA methylation in the rat amygdala

…, RA Cazuza, AJ Sales, ROG Carolino… - Molecular …, 2022 - journals.sagepub.com
Chronic pain increases the risk of developing anxiety, with limbic areas being likely neurological
substrates. Despite high clinical relevance, little is known about the precise behavioral, …

Anticonvulsant effects of the wasp Polybia ignobilis venom on chemically induced seizures and action on GABA and glutamate receptors

…, MR Mortari, L Oliveira, ROG Carolino… - … and Physiology Part C …, 2005 - Elsevier
Venoms of spiders and wasps are well recognized to present high affinity to the central
nervous tissue of many mammalian species. Here we describe the effects of direct exposure of …

Effects of estrogen therapy on the serotonergic system in an animal model of perimenopause induced by 4-vinylcyclohexen diepoxide (VCD)

N Pestana-Oliveira, B Kalil, CM Leite, ROG Carolino… - Eneuro, 2018 - eneuro.org
Chronic exposure to 4-vinylcycloxene diepoxide (VCD) in rodents accelerates the natural
process of ovarian follicular atresia modelling perimenopause in women. We investigated why …

Neurochemical characterization of a neuroprotective compound from Parawixia bistriata spider venom that inhibits synaptosomal uptake of GABA and glycine

…, R Guizzo, ACK Fontana, AB Pizzo, ROG Carolino… - Molecular …, 2006 - ASPET
The major contribution of this work is the isolation of a neuroprotective compound referred
to as 2-amino-5-ureidopentanamide (FrPbAII) (M r = 174) from Parawixia bistriata spider …

Glutamate binding is altered in hippocampus and cortex of Wistar rats after pilocarpine-induced Status Epilepticus

AOS Cunha, MR Mortari, ROG Carolino… - Neuroscience …, 2007 - Elsevier
Several evidences have pointed to biochemical alterations in some brain structures after
experimental Status Epilepticus (SE). Thus, the effects of pilocarpine-induced SE on the …

Nitric oxide synthase inhibitors improve prepulse inhibition responses of Wistar rats

AC Issy, M Lazzarini, RE Szawka, ROG Carolino… - Behavioural brain …, 2011 - Elsevier
INTRODUCTION: Cognitive and attentional deficits in schizophrenia include impairment of
the sensorimotor filter as measured by prepulse inhibition (PPI). In this way, the study of …

Atividade biológica e purificação parcial da neurotoxina da fruta Averhoa carambola L (Oxalidaceae)

ROG Carolino, J Coutinho Netto - 2002 - repositorio.usp.br
Metabólitos secundários estão presentes em todas as plantas e são os seus sistemas de
defesa contra insetos e herbívoros. Eles apresentam grande diversidade química, que é …

Evaluation of Thr6-bradykinin purified from Polybia occidentalis wasp venom in the choline uptake of mammal cortices

MR Mortari, AOS Cunha, ROG Carolino… - Pharmaceutical …, 2016 - Taylor & Francis
Context: Thr 6 -bradykinin is a peptide found in the venom of social and solitary wasps. This
kinin, along with other bradykinin-like peptides, is known to cause irreversible paralysis in …