User profiles for Rushang D. Patel
 | Rushang PatelFox Chase Cancer Center and Temple University, Philadelphia, PA Verified email at tuhs.temple.edu Cited by 774 |
[PDF][PDF] Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element‐independent manner
The aryl hydrocarbon receptor (AhR) is a ligand‐activated transcription factor. Activation of
AhR mediates the expression of target genes (eg, CYP1A1) by binding to dioxin response …
AhR mediates the expression of target genes (eg, CYP1A1) by binding to dioxin response …
[HTML][HTML] Ah receptor represses acute-phase response gene expression without binding to its cognate response element
RD Patel, IA Murray, CA Flaveny, A Kusnadi… - Laboratory …, 2009 - Elsevier
Repression of the nuclear factor-κB (NF-κB) pathway has been extensively researched
because of its pivotal role in inflammation. We investigated the potential of the aryl hydrocarbon …
because of its pivotal role in inflammation. We investigated the potential of the aryl hydrocarbon …
Evidence for an aryl hydrocarbon receptor-mediated cytochrome p450 autoregulatory pathway
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor responsible
for mediating the cellular response to the toxic compound 2,3,7,8,-tetrachlorodibenzo-p-dioxin. …
for mediating the cellular response to the toxic compound 2,3,7,8,-tetrachlorodibenzo-p-dioxin. …
[PDF][PDF] Aryl‐hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver
RD Patel, BD Hollingshead, CJ Omiecinski… - …, 2007 - Wiley Online Library
The aryl‐hydrocarbon receptor (AhR) is a basic helix‐loop‐helix/Per‐Arnt‐Sim transcription
factor that can be activated by exogenous as well as endogenous ligands. AhR is …
factor that can be activated by exogenous as well as endogenous ligands. AhR is …
The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is known to cause a large number of adverse
effects, mediated largely by its binding to the aryl-hydrocarbon receptor (AhR) and …
effects, mediated largely by its binding to the aryl-hydrocarbon receptor (AhR) and …
12 (R)-Hydroxy-5 (Z), 8 (Z), 10 (E), 14 (Z)-eicosatetraenoic acid [12 (R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor
The aryl hydrocarbon receptor (AHR) is a ligand-regulated transcription factor that can be
activated by structurally diverse chemicals, ranging from environmental carcinogens to dietary …
activated by structurally diverse chemicals, ranging from environmental carcinogens to dietary …
[HTML][HTML] Eltrombopag for treating thrombocytopenia after allogeneic stem cell transplantation
C Yuan, AM Boyd, J Nelson, RD Patel… - Biology of Blood and …, 2019 - Elsevier
Thrombocytopenia after allogeneic hematopoietic stem cell transplantation (allo-SCT) can
pose significant problems in management of patients. Eltrombopag is a small-molecule …
pose significant problems in management of patients. Eltrombopag is a small-molecule …
[HTML][HTML] Impact of next-generation sequencing cell-free pathogen DNA test on antimicrobial management in adults with hematological malignancies and transplant …
J Yu, JD Diaz, SC Goldstein, RD Patel… - … and Cellular Therapy, 2021 - Elsevier
Infections in adult patients with hematological malignancies (HM) and stem cell transplant (SCT)
recipients are a significant cause of morbidity and mortality. A timely diagnosis of …
recipients are a significant cause of morbidity and mortality. A timely diagnosis of …
Conditioning regimen intensity and low-dose azacitidine maintenance after allogeneic hematopoietic cell transplantation for acute myeloid leukemia
Azacitidine (AZA) maintenance following allogeneic hematopoietic cell transplantation (HCT)
for acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) may reduce …
for acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) may reduce …
[HTML][HTML] Comparison of myeloablative versus reduced-intensity conditioning regimens in allogeneic stem cell transplantation recipients with acute myelogenous …
The ideal conditioning intensity in allogeneic hematopoietic stem cell transplantation (HSCT)
is evolving. Previous prospective studies comparing myeloablative conditioning (MAC) …
is evolving. Previous prospective studies comparing myeloablative conditioning (MAC) …