… work, the steroid synthesis was triggered by exposing neurons to NMDA, which induced a
Ca 2+ influx through the NMDA receptors and resulted in the significant production of PREG(s) …

… effect was analyzed at 60 min via statistical analysis using anovas (*p < 0.05; **p < 0.01). …
From middle to right, blot of PRE with RC-19 (ERα) and synaptophysin IgG (S-Physin). At …

The cytochrome P-450 17α -hydroxylase, 17→20 lyase (P-450 17α ) is the key enzyme
responsible for the biosynthesis of androgens in steroidogenic organs. Its cellular localization …

Modulation of hippocampal synaptic plasticity by estrogen has been attracting much attention.
Here, we demonstrated the rapid effect of 17β-estradiol on the density and morphology of …

The THM growth technology for 100 mm diameter CdTe single crystals has been intensively
developed. In consequence of the optimization of growth conditions, we have succeeded in …

mRNA of cytochrome P450 21-hydroxylase (P450c21) is expressed in the brain, but little is
known about the enzymatic properties of P450c21 in the brain. In the present study, we …

… These steroids may be synthesized from a steroid precursor(s), such as pregnenolone or
other steroids, or from cholesterol, as so-called neurosteroids. The stimulation of estradiol and …

… S. Kominami and K. Amemiya are with Central Research Laboratory, Hitachi Ltd., Hitachi, …
Takahashi and S. Watanabe, “Recent progress in CdTe and CdZnTe detector,” IEEE Trans. …

We have recently demonstrated that the avian brain as well as the peripheral steroidogenic
glands produces pregnenolone, the main precursor of steroid hormones, on the basis of …

To clarify whether the amphibian brain synthesizes de novo neurosteroids, we examined
pregnenolone, pregnenolone sulfate ester, and cytochrome P450 side-chain cleavage enzyme …