User profiles for S Turcaud

Sébastien Turcaud

Meridiam
Verified email at meridiam.com
Cited by 659

Shape-programmed folding of stimuli-responsive polymer bilayers

G Stoychev, S Zakharchenko, S Turcaud… - ACS …, 2012 - ACS Publications
We investigated the folding of rectangular stimuli-responsive hydrogel-based polymer bilayers
with different aspect ratios and relative thicknesses placed on a substrate. It was found …

Hierarchical multi‐step folding of polymer bilayers

G Stoychev, S Turcaud, JWC Dunlop… - Advanced Functional …, 2013 - Wiley Online Library
… The progression of the diffusion front is slow (s) while the resultant mechanical actuation
is fast (ms). This enabled us to consider the two phenomena separately thereby neglecting …

Mixed-inhibitor-prodrug as a new approach toward systemically active inhibitors of enkephalin-degrading enzymes

MC Fournie-Zaluski, P Coric, S Turcaud… - Journal of medicinal …, 1992 - ACS Publications
… The separation of the two diastereoisomers constituting RB 101 showed that the analgesia
has a stereochemical dependence, the (S,S,S)-isomer being more active than the (Sfi,S)-…

Hole‐programmed superfast multistep folding of hydrogel bilayers

G Stoychev, L Guiducci, S Turcaud… - Advanced Functional …, 2016 - Wiley Online Library
… snapshot with exposure time of about 0.25 s (Movie_6_1, Supporting Information). We did
… than 0.25 s that is much smaller than the time of rolling of the edges on the films (2–3 s) that …

Inhibition of the enkephalin-metabolizing enzymes by the first systemically active mixed inhibitor prodrug RB 101 induces potent analgesic responses in mice and rats.

…, JM Soleilhac, E Soroca-Lucas, S Turcaud… - … of Pharmacology and …, 1992 - ASPET
N-([(R,S)-2-benzyl-3[(S)(2-amino-4-methylthio)butyl dithio]-1-oxopropyl)-L-phenylalanine
benzyl ester (RB101) is the first systemically active prodrug generating through a biologically …

Antidepressant-type effects of endogenous enkephalins protected by systemic RB 101 are mediated by opioid δ and dopamine D1 receptor stimulation

…, V Daugé, M Ruiz-Gayo, IG Fulga, S Turcaud… - European journal of …, 1992 - Elsevier
The role of endogenous enkephalins in behavioural control in mice was investigated by iv
injection of RB 101 (N-[(R,S)-2-benzyl-3[(S)(2-amino-4-methylthio) butyl dithio]-1-oxopropyl]-L-…

Potent and systemically active aminopeptidase N inhibitors designed from active-site investigation

MC Fournie-Zaluski, P Coric, S Turcaud… - Journal of medicinal …, 1992 - ACS Publications
… Since these /3-amino thiols are very small molecules, it was tempting to increase inhibition of
aminopeptidase N which prefers large substrates42 with catalytic site-directed compounds able …

Highly enantioselective asymmetric transfer hydrogenation: a practical and scalable method to efficiently access planar chiral [2.2] paracyclophanes

ML Delcourt, S Felder, S Turcaud… - The Journal of …, 2019 - ACS Publications
… p absolute configuration to the levorotatory product 2b and the S p one to aldehyde (−)-1b. …
The experimental ECD spectrum is compared to the computed spectrum of S p -7a in order to …

Pain-suppressive effects on various nociceptive stimuli (thermal, chemical, electrical and inflammatory) of the first orally active enkephalin-metabolizing enzyme …

…, O Valverde, R Maldonado, P Coric, S Turcaud… - Pain, 1997 - Elsevier
… The results obtained, which are confirmed in the present study, demonstrated that the (S)-…
of the NEP inhibitors on their in vivo activity, the (S)-isomers of the new inhibitors have been …

Synthesis and biological evaluation of a new derivative of bevirimat that targets the Gag CA-SP1 cleavage site

P Coric, S Turcaud, F Souquet, L Briant, B Gay… - European journal of …, 2013 - Elsevier
Bevirimat (2), the first-in-class HIV-1 maturation inhibitor, shows a low efficacy due
essentially to the natural polymorphism of its target, the CA-SP1 junction. Moreover, its low …