[HTML][HTML] Multiple forms of rat liver cytochrome P-450. Immunochemical evidence with antibody against cytochrome P-448.

PE Thomas, AY Lu, D Ryan, SB West, J Kawalek… - Journal of Biological …, 1976 - Elsevier
Purified hepatic cytochrome P-448 from 3-methylcholanthrene-treated rats was used to produce
antibody in rabbits. The cytochrome P-448 antibody (IgG fraction) isolated from immune …

Highly purified cytochrome P-448 and P-450 from rat liver microsomes

D Ryan, AYH Lu, J Kawalek, SB West… - … and biophysical research …, 1975 - Elsevier
Cytochrome P-448 from 3-methylcholanthrene-treated rats has been purified to a specific
content of greater than 20 nmoles/mg protein, and cytochrome P-450 from phenobarbital-…

[PDF][PDF] Immunochemical evidence for six forms of rat liver cytochrome P450 obtained using antibodies against purified rat liver cytochromes P450 and P448

PE THOMAS, AYH LU, D RYAN, SB WEST… - Molecular …, 1976 - Citeseer
b (19), NADPH-cytochrome c reductase … Plates A and B were made with 0.9% Agarose,
while plates C and D were made with 0.9% and 2.0% agar, respectively. Plate B is the same …

Reconstituted mammalian mixed-function oxidases: requirements, specificities and other properties

AYH Lu, SB West - Pharmacology & Therapeutics. Part A: Chemotherapy …, 1978 - Elsevier
Studies of mammalian mixed-function oxidase activity have been conducted with biological
systems ranging in complexity from the intact animal or perfused whole organ to isolated …

Role of cytochrome b5 in hydroxylation by a reconstituted cytochrome P-450-containing system

AYH Lu, SB West, M Vore, D Ryan, W Levin - Journal of Biological …, 1974 - ASBMB
1. The role of cytochrome b 5 in the oxidative metabolism of benzphetamine and 3,4-benzpyrene
in the presence of NADPH was studied with the reconstituted hydroxylation system …

[HTML][HTML] Separation, purification, and properties of multiple forms of cytochrome P-450 from the liver microsomes of phenobarbital-treated mice.

MT Huang, SB West, AY Lu - Journal of Biological Chemistry, 1976 - Elsevier
Four distinct cytochrome P-450 fractions (A1, A2, C1, and C2) have been separated and
purified from the liver microsomes of phenobarbital-treated hybrid mice (B6D2F1/J). Fractions …

A simple and rapid procedure for the purification of phenobarbitalinducible cytochrome P-450 from rat liver microsomes

SB West, MT Huang, GT Miwa, AYH Lu - Archives of Biochemistry and …, 1979 - Elsevier
A rapid and simple procedure has been developed for the purification of a phenobarbital-inducible
form of cytochrome P-450 from the liver microsomes of phenobarbitalpretreated rats. …

Accessibility of cytochrome P450 in microsomal membranes: inhibition of metabolism by antibodies to cytochrome P450

PE THOMAS, AYH LU, SB WEST, D RYAN… - Molecular …, 1977 - ASPET
Specific antibodies against highly purified cytochrome P450 from phenobarbital (PB)-treated
rats and cytochrome P448 from 3-methycholanthrene (MC)-treated rats were produced in …

Interferon-α2a in the treatment of acquired immunodeficiency syndrome-related Kaposi's sarcoma

…, H Goldsweig, PA Volberding, SB West… - Journal of …, 1991 - journals.lww.com
In a series of studies, recombinant interferon-[alpha] 2a (rIFN [alpha] 2a, Roferon-A) was
administered alone (273 men) or combined with vinblastine (91 men) to patients with acquired …

Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates: VI. Different substrate specificities of …

AYH Lu, W Levin, SB West, M Jacobson, D Ryan… - Journal of Biological …, 1973 - ASBMB
The substrate specificities of the liver microsomal cytochrome P450 fractions from control
and phenobarbital-treated immature, male rats were studied with the reconstituted …