Clinical Core of the Alzheimer's Disease Neuroimaging Initiative: progress and plans

…, R Raman, RG Thomas, S Walter… - Alzheimer's & …, 2010 - Wiley Online Library
The Clinical Core of the Alzheimer's Disease Neuroimaging Initiative (ADNI) has provided
clinical, operational, and data management support to ADNI since its inception. This article …

The Alzheimer's disease neuroimaging initiative: progress report and future plans

…, N Cairns, LA Beckett, A Toga, R Green, S Walter… - Alzheimer's & …, 2010 - Elsevier
The Alzheimer's Disease Neuroimaging Initiative (ADNI) beginning in October 2004, is a 6-year
research project that studies changes of cognition, function, brain structure and function, …

Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease

…, P Aisen, A Gamst, RG Thomas, M Donohue, S Walter… - Neurology, 2015 - AAN Enterprises
Objective: To compare the diagnostic accuracy of CSF biomarkers and amyloid PET for
diagnosing early-stage Alzheimer disease (AD). Methods: From the prospective, longitudinal …

Longitudinal associations of blood phosphorylated Tau181 and neurofilament light chain with neurodegeneration in Alzheimer disease

…, K Harless, J Salazar, Y Cabrera, S Walter… - JAMA …, 2021 - jamanetwork.com
Importance Plasma phosphorylated tau at threonine 181 (p-tau181) has been proposed as
an easily accessible biomarker for the detection of Alzheimer disease (AD) pathology, but its …

The mannose-binding lectin-pathway is involved in complement activation in the course of renal ischemia-reperfusion injury

B de Vries, SJ Walter, CJ Peutz-Kootstra… - The American journal of …, 2004 - Elsevier
Ischemia-reperfusion (I/R) is an important cause of acute renal failure (ARF). The complement
system appears to be essentially involved in I/R injury. However, via which pathway the …

Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity

…, RG Thomas, M Donohue, S Walter… - Proceedings of the …, 2013 - National Acad Sciences
Aberrant connectivity is implicated in many neurological and psychiatric disorders, including
Alzheimer’s disease and schizophrenia. However, other than a few disease-associated …

Calcitonin gene‐related peptide (CGRP) and migraine current understanding and state of development

ME Bigal, S Walter, AM Rapoport - Headache: The Journal of …, 2013 - Wiley Online Library
Calcitonin gene‐related peptide ( CGRP ) is a ubiquitous neuropeptide found at the very
centers of the migraine process, both centrally and peripherally. It has been under careful study …

[HTML][HTML] Early-stage Alzheimer disease: getting trial-ready

…, GA Jimenez-Maggiora, MS Rafii, S Walter… - Nature Reviews …, 2022 - nature.com
Slowing the progression of Alzheimer disease (AD) might be the greatest unmet medical
need of our time. Although one AD therapeutic has received a controversial accelerated …

Vascular burden and Alzheimer disease pathologic progression

…, P Aisen, A Gamst, RG Thomas, M Donohue, S Walter… - Neurology, 2012 - AAN Enterprises
Objective: To investigate the vascular contribution to longitudinal changes in Alzheimer
disease (AD) biomarkers. Methods: The Alzheimer's Disease Neuroimaging Initiative is a clinic …

Better verbal memory in women than men in MCI despite similar levels of hippocampal atrophy

…, P Aisen, A Gamst, RG Thomas, M Donohue, S Walter… - Neurology, 2016 - AAN Enterprises
Objective: To examine sex differences in the relationship between clinical symptoms related
to Alzheimer disease (AD) (verbal memory deficits) and neurodegeneration (hippocampal …