Microglia cells are the brain counterpart of macrophages and function as the first defense in
the brain. Although they are neuroprotective in the young brain, microglia cells may be …

It has been nearly a century since the early description of microglia by Rio-Hortega; since
then many more biological and pathological features of microglia have been recognized. …

Monoamine oxidase-B (MAO-B) inhibitors are commonly used for the symptomatic treatment
of Parkinson’s disease (PD). MAO-B inhibitor monotherapy has been shown to be effective …

Emerging evidences suggest that gut microbiota dysbiosis plays a role in Parkinson’s
disease (PD). However, the alterations in fecal microbiome in Chinese PD patients remains …

Paroxysmal kinesigenic dyskinesias is a paroxysmal movement disorder characterized by
recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary …

Parkinson’s disease (PD) is pathologically characterized by the presence of α-synuclein
positive intracytoplasmic inclusions. The missense mutation, A53T α-synuclein is closely related …

Previous studies have demonstrated altered metabolites in samples of Alzheimer’s disease (AD)
patients. However, the sample size from many of them is relatively small and the …

Background Increasing evidence suggests that microglial activation may participate in the
aetiology and pathogenesis of Parkinson's disease (PD). CD200-CD200R signalling has …

Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder.
Accumulating data indicate that astrocytes play an important role in the neuroinflammation …

Alzheimer’s disease (AD) is a neurodegenerative disorder that impairs mainly the memory
and cognitive function in elderly. Extracellular beta amyloid deposition and intracellular tau …