User profiles for Stephanie Chin

Stephanie Chin

Universiry of Toronto
Verified email at mail.utoronto.ca
Cited by 1181

Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

AP Wong, CE Bear, S Chin, P Pasceri… - Nature …, 2012 - nature.com
Cystic fibrosis (CF) is a fatal genetic disease caused by mutations in the CFTR (cystic fibrosis
transmembrane conductance regulator) gene, which regulates chloride and water transport …

Directed differentiation of cholangiocytes from human pluripotent stem cells

M Ogawa, S Ogawa, CE Bear, S Ahmadi, S Chin… - Nature …, 2015 - nature.com
Although bile duct disorders are well-recognized causes of liver disease, the molecular and
cellular events leading to biliary dysfunction are poorly understood. To enable modeling and …

Local variation in weather conditions influences incubation behavior and temperature in a passerine bird

BH Coe, ML Beck, SY Chin… - Journal of Avian …, 2015 - Wiley Online Library
Incubation is an important component of avian parental care and slight changes in incubation
temperature can affect offspring phenotype. Although many extrinsic and intrinsic factors …

[PDF][PDF] Acellular lung scaffolds direct differentiation of endoderm to functional airway epithelial cells: requirement of matrix-bound HS proteoglycans

S Shojaie, L Ermini, C Ackerley, J Wang, S Chin… - Stem cell reports, 2015 - cell.com
Efficient differentiation of pluripotent cells to proximal and distal lung epithelial cell
populations remains a challenging task. The 3D extracellular matrix (ECM) scaffold is a key …

Cascade organic solar cells

CW Schlenker, VS Barlier, SW Chin… - Chemistry of …, 2011 - ACS Publications
We demonstrate planar organic solar cells consisting of a series of complementary donor
materials with cascading exciton energies, incorporated in the following structure: glass/indium-…

Impact of Embodied Energy on materials/buildings with partial replacement of ordinary Portland Cement (OPC) by natural Pozzolanic Volcanic Ash

K Kupwade-Patil, C De Wolf, S Chin… - Journal of cleaner …, 2018 - Elsevier
This work studies the effect on Embodied Energy (EE) of concrete when Ordinary Portland
Cement (OPC) is partially substituted with natural Pozzolanic Volcanic Ash (VA) at the …

[HTML][HTML] Reduction and return of infectious trachoma in severely affected communities in Ethiopia

…, M Melese, Z Zhou, K Ray, S Chin… - PLoS neglected …, 2009 - journals.plos.org
Background Antibiotics are a major tool in the WHO's trachoma control program. Even a single
mass distribution reduces the prevalence of the ocular chlamydia that causes trachoma. …

Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells

AP Wong, S Chin, S Xia, J Garner, CE Bear… - nature protocols, 2015 - nature.com
Airway epithelial cells are of great interest for research on lung development, regeneration
and disease modeling. This protocol describes how to generate cystic fibrosis (CF) …

[HTML][HTML] Cardiac complications associated with COVID-19, MIS-C, and mRNA COVID-19 vaccination

SE Chin, SM Bhavsar, A Corson, ZJ Ghersin… - Pediatric cardiology, 2022 - Springer
The COVID-19 vaccine is now approved for individuals greater than 5 years of age, but
vaccination rates remain lower than expected in the pediatric age group. Misinformation and …

Health-related quality of life in children and young adults with Marfan syndrome

…, C Weismann, E Lawrence, S Chin… - The Journal of …, 2019 - Elsevier
Objective To assess health-related quality of life (HRQOL) in a large multicenter cohort of
children and young adults with Marfan syndrome participating in the Pediatric Heart Network …