The multitude of G-protein coupled receptor (GPR) superfamily cDNAs recently isolated has
exceeded the number of receptor subtypes anticipated by pharmacological studies. Analysis …

The psychosis associated with schizophrenia is characterized by alterations in sensory
processing and perception 1 , 2 . Some antipsychotic drugs were identified by their high affinity …

Tissue and cell-type identity lie at the core of human physiology and disease. Understanding
the genetic underpinnings of complex tissues and individual cell lineages is crucial for …

… Another departure from prior paradigms was our finding that c-fos was induced primarily in
… Milekic, and C. Gelernter Sealfon for their critical review of the manuscript; Harel Weinstein, …

GONADOTROPIN-RELEASING hormone plays a central role in the biology of reproduction (1),
and synthetic GnRH analogs have proven valuable in the treatment of a wide variety of …

We compared the accuracy of microarray measurements obtained with oligonucleotide
arrays (GeneChip, Affymetrix) with a laboratory-developed cDNA array by assaying test RNA …

Serotonin [5-hydroxytryptamine (5-HT)] neurotransmission in the central nervous system
modulates depression and anxiety-related behaviors in humans and rodents, but the …

GnRH plays a pivotal role in the reproductive system, and GnRH analogs have wide therapeutic
applications ranging from the treatment of prostatic cancer to infertility. Determination of …

Both antibodies and T cells contribute to immunity against influenza virus infection. However,
the generation of strong Th1 immunity is crucial for viral clearance. Interestingly, we found …

Influenza A virus (IAV) is a lytic virus in primary cultures of many cell types and in vivo. We
report that the kinase RIPK3 is essential for IAV-induced lysis of mammalian fibroblasts and …