Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain

…, QR LIU, B Hope, S Iwasaki, T Arinami… - Annals of the New …, 2006 - Wiley Online Library
Two well‐characterized cannabinoid receptors (CBrs), CB1 and CB2, mediate the effects of
cannabinoids and marijuana use, with functional evidence for other CBrs. CB1 receptors are …

Molecular genetics of febrile seizures

J Nakayama, T Arinami - Epilepsy research, 2006 - Elsevier
Febrile seizures (FSs) represent the most common form of childhood seizures, occurring in 2–5%
of infants in Europe and North America and in 6–9% in Japan. It has been recognized …

A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia

T Arinami, M Gao, H Hamaguchi… - Human molecular …, 1997 - academic.oup.com
An excess dopaminergic activity may be implicated in the etiology of schizophrenia. Our
objective was to identify nucleotide variants in the 5′ region of the dopamine D2 receptor gene …

Meta-analysis of 32 genome-wide linkage studies of schizophrenia

…, LE DeLisi, T Arinami, B Riley, T Paunio… - Molecular …, 2009 - nature.com
A genome scan meta-a nalysis (GSMA) was carried out on 32 independent genome-wide
linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases affected with …

[PDF][PDF] Mapping of a familial moyamoya disease gene to chromosome 3p24. 2-p26

…, T Sasaki, T Yoshimoto, M Fukui, T Arinami - The American Journal of …, 1999 - cell.com
Moyamoya disease is characterized by bilateral stenosis and/or occlusion of the terminal
portion of the internal carotid artery. Moyamoya disease is prevalent among patients <10 years …

Human cannabinoid receptor 1: 5′ exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse

…, J Hess, F Carillo, D Walther, ES Onaivi, T Arinami… - Molecular …, 2004 - nature.com
A number of lines of evidence make the gene that encodes the G-protein-coupled CB1/Cnr1
receptor a strong candidate to harbor variants that might contribute to individual differences …

Linkage and association of an interleukin 4 gene polymorphism with atopic dermatitis in Japanese families.

T Kawashima, E Noguchi, T Arinami… - Journal of medical …, 1998 - jmg.bmj.com
We examined linkage between markers at and near the IL4 gene and atopic dermatitis (AD)
in 88 Japanese nuclear families. Affected sib pair analysis suggested linkage between the …

[HTML][HTML] Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects

…, S Iwasaki, D Macharia, L Teasenfitz, T Arinami… - PLoS one, 2008 - journals.plos.org
Background Addiction and major depression are mental health problems associated with
stressful events in life with high relapse and reoccurrence even after treatment. Many …

Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia.

S Sohda, T Arinami, H Hamada, N Yamada… - Journal of medical …, 1997 - jmg.bmj.com
… reductase (MTHFR) gene, a C to T substitution at nucleotide 677, is responsible for reduced
… A common missense mutation in the MTHFR gene, a C to T substitution at nucleotide 677 …

[HTML][HTML] A novel susceptibility locus for moyamoya disease on chromosome 8q23

…, K Ikezaki, T Yoshimoto, M Fukui, T Arinami - Journal of human …, 2004 - nature.com
Moyamoya disease (MIM 252350) is characterized by stenosis or occlusion of the terminal
portions of the bilateral internal carotid arteries and by abnormal vascular networks at the …