Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain
Two well‐characterized cannabinoid receptors (CBrs), CB1 and CB2, mediate the effects of
cannabinoids and marijuana use, with functional evidence for other CBrs. CB1 receptors are …
cannabinoids and marijuana use, with functional evidence for other CBrs. CB1 receptors are …
Molecular genetics of febrile seizures
J Nakayama, T Arinami - Epilepsy research, 2006 - Elsevier
Febrile seizures (FSs) represent the most common form of childhood seizures, occurring in 2–5%
of infants in Europe and North America and in 6–9% in Japan. It has been recognized …
of infants in Europe and North America and in 6–9% in Japan. It has been recognized …
A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia
T Arinami, M Gao, H Hamaguchi… - Human molecular …, 1997 - academic.oup.com
An excess dopaminergic activity may be implicated in the etiology of schizophrenia. Our
objective was to identify nucleotide variants in the 5′ region of the dopamine D2 receptor gene …
objective was to identify nucleotide variants in the 5′ region of the dopamine D2 receptor gene …
Meta-analysis of 32 genome-wide linkage studies of schizophrenia
…, LE DeLisi, T Arinami, B Riley, T Paunio… - Molecular …, 2009 - nature.com
A genome scan meta-a nalysis (GSMA) was carried out on 32 independent genome-wide
linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases affected with …
linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases affected with …
[PDF][PDF] Mapping of a familial moyamoya disease gene to chromosome 3p24. 2-p26
…, T Sasaki, T Yoshimoto, M Fukui, T Arinami - The American Journal of …, 1999 - cell.com
Moyamoya disease is characterized by bilateral stenosis and/or occlusion of the terminal
portion of the internal carotid artery. Moyamoya disease is prevalent among patients <10 years …
portion of the internal carotid artery. Moyamoya disease is prevalent among patients <10 years …
Human cannabinoid receptor 1: 5′ exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse
…, J Hess, F Carillo, D Walther, ES Onaivi, T Arinami… - Molecular …, 2004 - nature.com
A number of lines of evidence make the gene that encodes the G-protein-coupled CB1/Cnr1
receptor a strong candidate to harbor variants that might contribute to individual differences …
receptor a strong candidate to harbor variants that might contribute to individual differences …
Linkage and association of an interleukin 4 gene polymorphism with atopic dermatitis in Japanese families.
T Kawashima, E Noguchi, T Arinami… - Journal of medical …, 1998 - jmg.bmj.com
We examined linkage between markers at and near the IL4 gene and atopic dermatitis (AD)
in 88 Japanese nuclear families. Affected sib pair analysis suggested linkage between the …
in 88 Japanese nuclear families. Affected sib pair analysis suggested linkage between the …
[HTML][HTML] Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects
…, S Iwasaki, D Macharia, L Teasenfitz, T Arinami… - PLoS one, 2008 - journals.plos.org
Background Addiction and major depression are mental health problems associated with
stressful events in life with high relapse and reoccurrence even after treatment. Many …
stressful events in life with high relapse and reoccurrence even after treatment. Many …
Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia.
S Sohda, T Arinami, H Hamada, N Yamada… - Journal of medical …, 1997 - jmg.bmj.com
… reductase (MTHFR) gene, a C to T substitution at nucleotide 677, is responsible for reduced
… A common missense mutation in the MTHFR gene, a C to T substitution at nucleotide 677 …
… A common missense mutation in the MTHFR gene, a C to T substitution at nucleotide 677 …
[HTML][HTML] A novel susceptibility locus for moyamoya disease on chromosome 8q23
…, K Ikezaki, T Yoshimoto, M Fukui, T Arinami - Journal of human …, 2004 - nature.com
Moyamoya disease (MIM 252350) is characterized by stenosis or occlusion of the terminal
portions of the bilateral internal carotid arteries and by abnormal vascular networks at the …
portions of the bilateral internal carotid arteries and by abnormal vascular networks at the …