The role of inflammation in epilepsy
… following seizures might direct blood leukocytes into the brain, 92 which would be consistent
with the reported emergence of granulocytes during epileptogenesis, 63,92 and sparse T …
with the reported emergence of granulocytes during epileptogenesis, 63,92 and sparse T …
Neuropeptides: opportunities for drug discovery
T Hökfelt, T Bartfai, F Bloom - The Lancet Neurology, 2003 - thelancet.com
The role of peptides as signalling molecules in the nervous system has been studied for more
than 30 years. Neuropeptides and their G-protein-coupled receptors are widely distributed …
than 30 years. Neuropeptides and their G-protein-coupled receptors are widely distributed …
[PDF][PDF] Cytokines and fever
B Conti, I Tabarean, C Andrei, T Bartfai - Front Biosci, 2004 - researchgate.net
… are the findings that cell penetrating ceramide analogs such as C2 ceramide can in vivo
mediate fever like rise in temperature when applied intracerebroventricularly (Bartfai et al., …
mediate fever like rise in temperature when applied intracerebroventricularly (Bartfai et al., …
Interleukin-1β enhances NMDA receptor-mediated intracellular calcium increase through activation of the Src family of kinases
…, A Vezzani, MM Behrens, T Bartfai… - Journal of …, 2003 - Soc Neuroscience
Interleukin (IL)-1β is a proinflammatory cytokine implicated in various pathophysiological
conditions of the CNS involving NMDA receptor activation. Circumstantial evidence suggests …
conditions of the CNS involving NMDA receptor activation. Circumstantial evidence suggests …
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo
…, XJ Xu, Z Wiesenfeld-Hallin, T Hökfelt, T Bartfai… - Nature …, 1998 - nature.com
… City, CA) peptide synthesizer using the t-Boc strategy of solid phase peptide synthesis“.
PNA oligomers were synthesized manually” using the tBoc strategy. The purity of peptides and …
PNA oligomers were synthesized manually” using the tBoc strategy. The purity of peptides and …
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis
…, LB Lovat, T Bartfai, A Alanine, C Hertel, T Hoffmann… - Nature, 2002 - nature.com
The normal plasma protein serum amyloid P component (SAP) binds to fibrils in all types of
amyloid deposits, and contributes to the pathogenesis of amyloidosis. In order to intervene in …
amyloid deposits, and contributes to the pathogenesis of amyloidosis. In order to intervene in …
Powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in mice
…, J Lundkvist, K Iverfeldt, T Bartfai - Proceedings of the …, 2000 - National Acad Sciences
IL-1β and its endogenous receptor antagonist (IL-1Ra) are rapidly induced by seizures in
the rodent hippocampus. Exogenously applied IL-1β prolongs seizures in an IL-1R type I-…
the rodent hippocampus. Exogenously applied IL-1β prolongs seizures in an IL-1R type I-…
Interleukin‐1β contributes to the generation of experimental febrile seizures
…, A Vezzani, M Behrens, T Bartfai… - Annals of Neurology …, 2005 - Wiley Online Library
… Differences among groups were analyzed using Student's t test or one-way analysis of
variance, as appropriate, followed by Bonferroni post hoc test. Significance = 0.05. Values are …
variance, as appropriate, followed by Bonferroni post hoc test. Significance = 0.05. Values are …
Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice.
Z Chai, S Gatti, C Toniatti, V Poli, T Bartfai - The Journal of experimental …, 1996 - rupress.org
Interleukin (IL)-6, IL-1 beta, and tumor necrosis factor alpha (TNF-alpha) are considered to
act as endogenous pyrogens. Because of the complex pattern of cross-inductions between …
act as endogenous pyrogens. Because of the complex pattern of cross-inductions between …
[HTML][HTML] A blood based 12-miRNA signature of Alzheimer disease patients
Background Alzheimer disease (AD) is the most common form of dementia but the identification
of reliable, early and non-invasive biomarkers remains a major challenge. We present a …
of reliable, early and non-invasive biomarkers remains a major challenge. We present a …