At many central excitatory synapses, AMPA receptors relay the electrical signal, whereas
activation of NMDA receptors is conditional and serves a modulatory function. We show here …

Thyroid hormone is important in the regulation of synthesis and secretion of thyroid-stimulating
hormone (TSH) in the anterior pituitary, but its role in the control of hypothalamic …

The amphibian tetradecapeptide bombesin and its mammalian homolog gastrin-releasing
peptide are neurotransmitters and paracrine hormones, and are mitogenic for fibroblast and …

The metabotropic glutamate receptor (mGluR) cDNAs were originally cloned from rat,
except for the mouse cDNA clone encoding mGluR8. Mouse mGluR8 couples weakly to the …

Despite the cloning of several metabotropic glutamate receptors (mGluR1-6), the activity
and localization of the cloned mGluRs do not account for the action of L-2-amino-4-…

Publisher Summary The bombesin-like peptides comprise a large family of peptides
common to frogs and man. Bombesin when injected into rats proved to have a wide variety of …

The large number of metabotropic glutamate receptor subtypes suggests diverse roles in
brain function, although specific distribution patterns can give clues to subtype-specific …

… Lechan RM, Segerson TP, Pro-TRH gene expression and precursor peptides in rat brain:
observations by hybridization analysis and immunocytochemistry. Ann NY Acad Sci, in press 4. …

Receptor-mediated activation of a G-protein-coupled inwardly rectifying potassium channel (GIRK)
is a common mechanism for synaptic modulation in the CNS. However, evidence for …

We studied the distribution of pro-TRH mRNA in rat brain by in situ hybridization histochemistry
using radiolabeled single stranded cRNA probes to confirm the hypothesis that the TRH …