Interactions of leucine enkephalin and narcotics with opioid receptors

JL VAUGHT, T KITANO, AE Takemori - Molecular Pharmacology, 1981 - ASPET
In superfusion experiments in vitro, facilitation of naloxone-releasable morphine was
observed with slices of corpus striatum which were obtained from mice pretreated in vivo with …

STUDIES ON PHARMACODYNAMIC ACTION OF N-ETHYLMALEIMIDE (NEM) 1ST REPORT: INFLUENCE OF NEM ON SYNAPTIC TRANSMISSION OF …

H Yamamoto, T KITANO, H NISHINO… - The Japanese Journal …, 1973 - jstage.jst.go.jp
In isolated guinea pig atrial preparations, NEM in the concentration of 5•~ 10-5 M to 10-4 M
produced an increase in the amplitude and rate of contraction at earlier stages, resulting in …

Differential effects of Leu-and Met-enkephalin on narcotic-induced enhancement of naloxone efficacy

AE Takemori, JL VAUGHT, T KITANO - Endogenous and Exogenous …, 1980 - Elsevier
In superfusion experiments in vitro, facilitation of naloxone-releasable morphine was observed
with slices of corpus striatum which were obtained from mice pretreated in vivo with 20 mg…

Comparative study on pharmacological properties of sultopride, sulpiride and other antipsychotic drugs: Influences of sultopride, sulpiride and other antipsychotic …

K Horikomi, Y Takahashi, K Ozeki, T Kitano - Japanese Journal of …, 1983 - Elsevier
In order to elucidate pharmacological properties of sultopride and sulpiride, their effects on
the locomotor hyperactivity induced by apomorphine in mice were examined by use of photo-…

[CITATION][C] Further studies on the enhanced affinity of opioid receptors for naloxone in morphine-dependent mice.

T Kitano, AE Takemori - Journal of Pharmacology and Experimental …, 1979 - ASPET
Further studies on the enhanced affinity of opioid receptors for naloxone in morphine-
dependent mice.

Studies on pharmacodynamic action of N-ethylmaleimide (NEM)-1-Influence of NEM on synaptic transmission of sympathetic nerves in guinea pigs

Y Hiroyuki, K Takafumi, N Hitoo, M Tadashi - Jpn. J. Pharmacol., 1973 - cir.nii.ac.jp
In isolated guinea pig atrial preparations, NEM in the concentration of 5× 10-5 M to 10-4 M
produced an increase in the amplitude and rate of contraction at earlier stages, resulting in …

Comparison of diagnostic accuracy for nonocclusive mesenteric ischemia in models with biomarkers including intestinal fatty acid–binding protein in addition to …

…, H Funaoka, T Funabiki, T Saida, M Kitano - Journal of Trauma …, 2019 - journals.lww.com
BACKGROUND Nonocclusive mesenteric ischemia (NOMI) is an acute and life-threatening
gastrointestinal disorder, requiring rapid therapeutic intervention for ischemic bowel. …

[HTML][HTML] Phase I study of the indoleamine 2, 3-dioxygenase 1 inhibitor navoximod (GDC-0919) as monotherapy and in combination with the PD-L1 inhibitor …

…, S Iwasa, K Yonemori, A Shimomura, S Kitano… - Investigational New …, 2020 - Springer
Navoximod (GDC-0919) is a small molecule inhibitor of indoleamine-2,3-dioxygenase 1. This
study investigated the safety, tolerability and pharmacokinetics of navoximod alone and in …

[HTML][HTML] Macrophage accumulation within coronary arterial wall in diabetic patients with acute coronary syndrome: a study with in-vivo intravascular imaging …

T Kogo, T Hiro, D Kitano, T Takayama… - Cardiovascular …, 2020 - Springer
Background and aims Macrophage accumulation in arteriosclerotic plaque of coronary arteries
is involved in plaque destabilization. Atherosclerosis has been known to be progressive …

Abstract CT062: A phase 1 study of tamnorzatinib (ONO-7475), an Axl/Mer dual inhibitor, alone and in combination with nivolumab in patients with advanced or …

Y Katsuya, K Yonemori, T Shimizu, T Koyama, S Kitano… - Cancer Research, 2024 - AACR
Background: Tamnorzatinib (ONO-7475) is an orally active small molecule Axl/Mer dual
inhibitor that not only directly acts on cancer cells to suppress their proliferation, but also on …